CAJ | 학술논문

目的：探讨厄贝沙坦联合阿托伐他汀在原发性高血压患者左心室肥厚中的临床治疗效果。方法选择2010年12月～2012年12月住院的52例原发性高血压患者左心室肥厚作为研究对象，按照系统随机化分为两组，对照组24例常规治疗基础上予以厄贝沙坦治疗，观察组28例常规治疗基础上联合厄贝沙坦、阿托伐他汀治疗，观察比较两组的临床治疗效果。结果两组经过治疗后的血压及左心室质量指数得到显著改善，观察组的改善效果明显好于对照组，差异比较均具有统计学意义（p ＜0．05），观察组治疗有效率为96.43％，对照组的治疗有效率为83.33％，组间比较差异具统计学意义（p＜0.05）。结论厄贝沙坦联合阿托伐他汀是治疗原发性高血压患者左心室肥厚的有效用药方案，值得临床推广应用。
목적：탐토액패사탄연합아탁벌타정재원발성고혈압환자좌심실비후중적림상치료효과。방법선택2010년12월～2012년12월주원적52례원발성고혈압환자좌심실비후작위연구대상，안조계통수궤화분위량조，대조조24례상규치료기출상여이액패사탄치료，관찰조28례상규치료기출상연합액패사탄、아탁벌타정치료，관찰비교량조적림상치료효과。결과량조경과치료후적혈압급좌심실질량지수득도현저개선，관찰조적개선효과명현호우대조조，차이비교균구유통계학의의（p ＜0．05），관찰조치료유효솔위96.43％，대조조적치료유효솔위83.33％，조간비교차이구통계학의의（p＜0.05）。결론액패사탄연합아탁벌타정시치료원발성고혈압환자좌심실비후적유효용약방안，치득림상추엄응용。
Objective To discuss the clinical effect of irbesartan combined with atorvastin on LVH in EH patients. Methods 52 EH patients with LVH during December 2010 and December 2012 were chosen as research objects and ran-domly divided into 2 groups.Control group (24 cases) was treated with irbesartan on basis of routine treatment while observa-tion group (28 cases) was treated with irbesartan combined atorvastin on basis of routine treatment.Clinical effects of the 2 groups were observed and compared.Results After treatment, BP and LVMI of the 2 groups both improved obviously and the improvement effect of observation group was better than control group (p<0.05).Clinical effective rate of observation group was 96.43% while control group was 83.33% (p<0.05).Conclusion Irbesartan combined atorvastin is an effective medi-cation method for treatment of LVH of patients with EH and is worth of being popularized in clinical work.