CAJ | 학술논문

目的：了解静宁县15岁以下人群乙肝疫苗接种现状、乙肝病毒标志物的分布情况及影响因素，为采取进一步控制措施提供依据。方法：采取整群分层随机抽样的方法，抽取本辖区7个乡镇的15岁以下的1260人作为调查对象，检测HBsAg、抗-HBs、抗-HBc等HBV感染标志物，以问卷和查验预防接种证或卡片的方式对乙肝疫苗接种率进行调查。结果：15岁以下人群HBsAg、抗-HBs和抗-HBc阳性率分别为0.95%、78.97%、5.16%，HBV感染率为6.98%。HBsAg、抗-HBc阳性率和HBV感染率随年龄增长而升高（P<0.05）。15岁以下人群乙肝疫苗全程接种率为90.95%，随年龄的增加而逐渐降低（χ2趋势=60.569，P=0.000）。结论：15岁以下人群HBV感染率已处于较低水平，乙肝保护性抗体水平随年龄的减小而升高；乙肝疫苗接种是乙肝病毒感染的保护因素，年龄是乙肝病毒感染的危险因素。
목적：료해정저현15세이하인군을간역묘접충현상、을간병독표지물적분포정황급영향인소，위채취진일보공제조시제공의거。방법：채취정군분층수궤추양적방법，추취본할구7개향진적15세이하적1260인작위조사대상，검측HBsAg、항-HBs、항-HBc등HBV감염표지물，이문권화사험예방접충증혹잡편적방식대을간역묘접충솔진행조사。결과：15세이하인군HBsAg、항-HBs화항-HBc양성솔분별위0.95%、78.97%、5.16%，HBV감염솔위6.98%。HBsAg、항-HBc양성솔화HBV감염솔수년령증장이승고（P<0.05）。15세이하인군을간역묘전정접충솔위90.95%，수년령적증가이축점강저（χ2추세=60.569，P=0.000）。결론：15세이하인군HBV감염솔이처우교저수평，을간보호성항체수평수년령적감소이승고；을간역묘접충시을간병독감염적보호인소，년령시을간병독감염적위험인소。
Distribution and relative fators of hepatitis B vaccination and marker of hepatitis B virus were observed in children under 15 years old, which provide scientific data for prevention. Methods:Cluster sampling and stratified random sampling were used to selected 1260 individuals under 15 years old from 7 towns for study in which HBsAg, anti-HBs, anti-HBc and other HBV infection markers were respectively detected,and questionnaire investigation, examination of vaccination certificate or card were used to assess hepatitis B vaccination rate. Results:HbsAg, anti-HBs, anti-HBc positive rates and HBV infection rate in children under 15 years old respectively were 0.95%, 78.97%, 5.16%and 6.98%, which was increased with age(P<0.05). Hepatitis B vaccine coverage rate was 90.95%, which was reduced with age(χ2=60.596, P=0.000). Conclusion:HBV infection rate is a lower level in children under 15 years old. Levels of protective antibodies to hepatitis B are reduced with age. Hepatitis B vaccination is a protective factor for hepatitis B virus infection, but age is a risk factor.