临床肺科杂志
臨床肺科雜誌
림상폐과잡지
JOUNAL OF CLINICAL PULMONARY MEDICINE
2014年
9期
1572-1575
,共4页
薛青%焦维克%邓新宇%甘玉燕%方桂桔%王陈金%李树奇%张灿辉%吴建辉
薛青%焦維剋%鄧新宇%甘玉燕%方桂桔%王陳金%李樹奇%張燦輝%吳建輝
설청%초유극%산신우%감옥연%방계길%왕진금%리수기%장찬휘%오건휘
慢性阻塞性肺疾病%国际勃起功能指数量表%勃起功能障碍%性功能%睾酮
慢性阻塞性肺疾病%國際勃起功能指數量錶%勃起功能障礙%性功能%睪酮
만성조새성폐질병%국제발기공능지수량표%발기공능장애%성공능%고동
pulmonary disease%chronic obstructive%IIEF-5%erectile dysfunction%sexuality%testosterone
目的:研究COPD患者合并勃起功能障碍( ED)的发生率。方法对顺序纳入2010年7月~2012年7月宁德市医院门诊就诊的符合入选标准的男性COPD稳定期患者86例进行临床评估,年龄44~70岁,平均(62.28±6.44)岁;同时选取相匹配的对照组30名。所有受试者均进行肺功能测定[包括用力肺活量( FVC%)、第一秒用力呼气容积( FEV1%)、一秒率( FEV1/FVC%)和一氧化碳弥散量( DLco%)]、6分钟步行试验(6MWT)、指端血氧饱和度测定(SaO2)和血清性激素[血清睾酮(T)和雌二醇(E2)水平]检测,同时通过回答国际勃起功能指数-5(IIEF-5)问卷来诊断和评估ED。结果 COPD组总的ED发病率70%,对照组67%。与对照组相比,COPD组血清睾酮水平明显降低[分别为(4.63±1.70)和(3.57±1.52)],而血清雌二醇水平差别无统计学差异[分别为(25.45±8.35)和(22.95±6.17)]。相比对照组,COPD组中、重度ED的发生率更高[分别为14%和42%],并且ED的分值更低、程度更重[ ED分值分别为(17.91±7.90)和(12.66±8.44);ED程度值分别为(2.53±1.49)和(1.66±0.71)]。 COPD组ED的分值与年龄无相关性,但与吸烟、病程、6MWD、FEV1%、DLco、SaO2、T指标相关,且均有统计学意义。结论 COPD患者较同年龄的健康对照组ED的发生更加频繁且严重,对COPD综合评估和管理时应引起重视。
目的:研究COPD患者閤併勃起功能障礙( ED)的髮生率。方法對順序納入2010年7月~2012年7月寧德市醫院門診就診的符閤入選標準的男性COPD穩定期患者86例進行臨床評估,年齡44~70歲,平均(62.28±6.44)歲;同時選取相匹配的對照組30名。所有受試者均進行肺功能測定[包括用力肺活量( FVC%)、第一秒用力呼氣容積( FEV1%)、一秒率( FEV1/FVC%)和一氧化碳瀰散量( DLco%)]、6分鐘步行試驗(6MWT)、指耑血氧飽和度測定(SaO2)和血清性激素[血清睪酮(T)和雌二醇(E2)水平]檢測,同時通過迴答國際勃起功能指數-5(IIEF-5)問捲來診斷和評估ED。結果 COPD組總的ED髮病率70%,對照組67%。與對照組相比,COPD組血清睪酮水平明顯降低[分彆為(4.63±1.70)和(3.57±1.52)],而血清雌二醇水平差彆無統計學差異[分彆為(25.45±8.35)和(22.95±6.17)]。相比對照組,COPD組中、重度ED的髮生率更高[分彆為14%和42%],併且ED的分值更低、程度更重[ ED分值分彆為(17.91±7.90)和(12.66±8.44);ED程度值分彆為(2.53±1.49)和(1.66±0.71)]。 COPD組ED的分值與年齡無相關性,但與吸煙、病程、6MWD、FEV1%、DLco、SaO2、T指標相關,且均有統計學意義。結論 COPD患者較同年齡的健康對照組ED的髮生更加頻繁且嚴重,對COPD綜閤評估和管理時應引起重視。
목적:연구COPD환자합병발기공능장애( ED)적발생솔。방법대순서납입2010년7월~2012년7월저덕시의원문진취진적부합입선표준적남성COPD은정기환자86례진행림상평고,년령44~70세,평균(62.28±6.44)세;동시선취상필배적대조조30명。소유수시자균진행폐공능측정[포괄용력폐활량( FVC%)、제일초용력호기용적( FEV1%)、일초솔( FEV1/FVC%)화일양화탄미산량( DLco%)]、6분종보행시험(6MWT)、지단혈양포화도측정(SaO2)화혈청성격소[혈청고동(T)화자이순(E2)수평]검측,동시통과회답국제발기공능지수-5(IIEF-5)문권래진단화평고ED。결과 COPD조총적ED발병솔70%,대조조67%。여대조조상비,COPD조혈청고동수평명현강저[분별위(4.63±1.70)화(3.57±1.52)],이혈청자이순수평차별무통계학차이[분별위(25.45±8.35)화(22.95±6.17)]。상비대조조,COPD조중、중도ED적발생솔경고[분별위14%화42%],병차ED적분치경저、정도경중[ ED분치분별위(17.91±7.90)화(12.66±8.44);ED정도치분별위(2.53±1.49)화(1.66±0.71)]。 COPD조ED적분치여년령무상관성,단여흡연、병정、6MWD、FEV1%、DLco、SaO2、T지표상관,차균유통계학의의。결론 COPD환자교동년령적건강대조조ED적발생경가빈번차엄중,대COPD종합평고화관리시응인기중시。
Objective To investigate the erectile dysfunction in patients with COPD. Methods 86 male patients with COPD were selected in this study, aging from 44 to 70 years old, with an average of 62. 28 ± 6. 44. 30 healthy people were taken as controls. Their lung function were detected, including FVC%, FEV1%, FEV1/FVC%, DLco%, 6MWT, SaO2 and T and E2. They were asked to answer the International Index of Erectile Func-tion 5 (IIEF-5) questionnaire as a method to diagnose and classify ED. Results The serum level of testosterone in the COPD group was lower than that in the control group, but the serum level of estradiol showed no significant differ-ence between the two groups. The incidence of ED was obviously higher in the patients with moderate and severe COPD than others. The score of ED of COPD patients was not correlated with age and estradiol levels, but correlated with smoking burden, duration of COPD, FEV1%, DLco, SaO2, 6MWD and testosterone level. Conclusion The present study shows that ED is frequent and more severe in COPD patients than age-matched controls. Patients with COPD need comprehensive management including a detailed sexual evaluation.