CAJ | 학술논문

目的：检测海珠喘息定片中是否含糖皮质激素，并对其在支气管哮喘中的临床应用进行评价。方法：采用薄层色谱法、四氮唑盐鉴别法进行检测。依据国家食品药品监督管理总局颁布的规范，对海珠喘息定片说明书进行综合分析，并评价其在支气管哮喘中的临床应用。结果：海珠喘息定片中未检测到糖皮质激素，但长期使用可出现耐受现象，增加不良反应的发生率，同时海珠喘息定片说明书存在部分缺项。结论：支气管哮喘患者不宜长期口服海珠喘息定片。
목적：검측해주천식정편중시부함당피질격소，병대기재지기관효천중적림상응용진행평개。방법：채용박층색보법、사담서염감별법진행검측。의거국가식품약품감독관리총국반포적규범，대해주천식정편설명서진행종합분석，병평개기재지기관효천중적림상응용。결과：해주천식정편중미검측도당피질격소，단장기사용가출현내수현상，증가불량반응적발생솔，동시해주천식정편설명서존재부분결항。결론：지기관효천환자불의장기구복해주천식정편。
Objietive:Detection of glucocorticoid in Haizhu Chuanxiding Tablets and to evaluate the clinical application in bronchial asthma. Methods:Detection of glucocorticoid by TLC and MTT.According to a specification issued by China Food and Drug Administration, the directions of Haizhu Chuanxiding Tablets was analyzed and to evaluate the clinical application in bronchial asthma. Results:Glucocorticoid was not detected in Haizhu Chuanxiding Tablets,but long-term use can have tolerance,increase the incidence of adverse reaction,at the same time, the directions of Haizhu Chuanxiding Tablets are missing. Conclusions:Patients with bronchial asthma should not chronically use Haizhu Chuanxiding Tablets.