CAJ | 학술논문

目的：研究SPECT/CT断层融合在继发性甲状旁腺功能亢进症（SHPT）中的诊断价值，初步探讨影响甲状旁腺显像的因素。方法 SHPT患者35例，采用双时相法显像，5min、30min早期显像及1h、2h延迟平面显像，2h后平面显像后随即行颈胸部99mTc-MIBI SPECT/CT同机融合显像。平面显像与静态显像相比较35例，术后病理相比较29例，并结合患者的临床表现及实验室指标进行统计分析，对平面和SPECT/CT显像的诊断阳性率行χ2检验。结果平面显像诊断阳性率为71．43％（25/35），断层阳性率91．43％（32/35）。平面显像和SPECT/CT对继发性甲状旁腺功能亢进诊断的差异有统计学意义（χ2＝5．1429，P＜0．05）。结论 SPECT/CT显像比面显像更能有效的甄别继发性甲状旁腺的基础上增加了核素融合和CT诊断信息，可以显示病变部位的更细微的定位结构，明显提高了对甲状旁腺病变诊断的阳性率。
목적：연구SPECT/CT단층융합재계발성갑상방선공능항진증（SHPT）중적진단개치，초보탐토영향갑상방선현상적인소。방법 SHPT환자35례，채용쌍시상법현상，5min、30min조기현상급1h、2h연지평면현상，2h후평면현상후수즉행경흉부99mTc-MIBI SPECT/CT동궤융합현상。평면현상여정태현상상비교35례，술후병리상비교29례，병결합환자적림상표현급실험실지표진행통계분석，대평면화SPECT/CT현상적진단양성솔행χ2검험。결과평면현상진단양성솔위71．43％（25/35），단층양성솔91．43％（32/35）。평면현상화SPECT/CT대계발성갑상방선공능항진진단적차이유통계학의의（χ2＝5．1429，P＜0．05）。결론 SPECT/CT현상비면현상경능유효적견별계발성갑상방선적기출상증가료핵소융합화CT진단신식，가이현시병변부위적경세미적정위결구，명현제고료대갑상방선병변진단적양성솔。
Objective To evaluate the clinical value of 99m Tc -MIBI SPECT/CT imaging for diagnosis of secondary hyperparathyroidism(SHPT),and to investigate the effect of possible factors on the parathyroid imaging.Methods A total of 35 patients were selected inthis study.Five minutes,thirty minutes (early phase)and two hours (delayed phase)after intravenous injection of 99m Tc-MIBI(740MBq),dual -phase planar imaging was performed,followed by SPECT/CT imaging over neck and chest.Thirty -five SHPT patientswere compared by both planar imaging and SPECT/CT imaging,while diagnosis of twenty -nine patients included was confirmed by pa-thology.χ2 -test was used to compare the results of planar and SPECT/CT imaging using SPSS 16.0 software.Results Compared to71.43%(25 /35)of the positive rate in planar imaging,the positive rate of the SPECT/CT imaging was 91.43%(32 /35).Difference inthe positive rates between planar and SPECT/CT imaging was statistically significant(χ2 =5.1429,P <0.05).Conclusions SPECT/CT imaging is more efficient than planar imaging for the fusion imaging and CT diagnosis of parathyroid glands with secondary hyperpar-athyroidism.SPECT/CT parathyroid imaging combined with CT scan can provide more information about localization of the lesions,which highly improve the positive rate of parathyroids.