CAJ | 학술논문

目的探讨肝移植术后肿瘤复发对于移植患者术后长期生存的影响。方法回顾性分析解放军总医院2007年1月至2009年12月101例因肝脏恶性肿瘤行肝移植术患者的临床资料，随访终点为2012年12月，并对随访过程中死亡患者的资料进行分析。结果本院恶性肿瘤患者行肝移植术后1年生存率已达到80%左右，3年生存率已达到70%左右。随访至2012年12月，死亡35例，其中肿瘤复发是导致患者死亡的首要因素，达到45.7%，术后出血占第二位，达到28.6%。结论肿瘤复发已成为影响恶性肿瘤患者肝移植术后长期存活的主要因素，如何预防和减少肿瘤复发率是今后肝移植工作的重点。
목적탐토간이식술후종류복발대우이식환자술후장기생존적영향。방법회고성분석해방군총의원2007년1월지2009년12월101례인간장악성종류행간이식술환자적림상자료，수방종점위2012년12월，병대수방과정중사망환자적자료진행분석。결과본원악성종류환자행간이식술후1년생존솔이체도80%좌우，3년생존솔이체도70%좌우。수방지2012년12월，사망35례，기중종류복발시도치환자사망적수요인소，체도45.7%，술후출혈점제이위，체도28.6%。결론종류복발이성위영향악성종류환자간이식술후장기존활적주요인소，여하예방화감소종류복발솔시금후간이식공작적중점。
Objective To explore the impact of tumor recurrence to long term survival after liver transplantation. Methods We retrospectively analyzed the clinical data of 101 cases with liver tumor after liver transplantation between January 2007 and December 2009. The end of follow-up data was December 2012,and the data of dead patients were analyzed. Results The one year survival rate after liver transplantation of malignant tumor patients was about 80%,and the three years survival rate was about 70%. Follow up to December 2012, 35 cases were dead. The first important reason to lead patients dead was tumor recurrence,and the rate was 45.7%. The next reason was hemorrhage,with the rate of 28.6%. Conclusions Tumor recurrence has already been thought to be the significant element impacting the long term survival of liver transplant recipients with primary malignancy. And the clinical emphasis has lied on the prevention of the tumor recurrence and decreasing its rate.