CAJ | 학술논문

目的：对精子活力和形态与常规IVF-ET胚胎质量的关系进行探讨。方法分析251对在本中心接受IVF治疗的不孕夫妇男方患者前向运动精子总数和精子正常形态百分率对IVF受精率、卵裂率、优质胚胎率、种植率和早期流产率的影响。结果当前向运动精子总数＜20×106时，卵裂率、优质胚胎率显著低于活力正常组（P＜0．05），对IVF受精率、种植率、临床妊娠率、早期流产率无影响（P＞0．05）；当精子正常形态百分率＜4％时，受精率显著低于精子形态正常组（P＜0．05），对卵裂率、优质胚胎率、临床妊娠率、种植率和早期流产率无影响（ P＞0．05）。结论精子活力和形态与胚胎有一定关系，但是仅凭精子活力和形态预测胚胎质量有一定局限性。
목적：대정자활력화형태여상규IVF-ET배태질량적관계진행탐토。방법분석251대재본중심접수IVF치료적불잉부부남방환자전향운동정자총수화정자정상형태백분솔대IVF수정솔、란렬솔、우질배태솔、충식솔화조기유산솔적영향。결과당전향운동정자총수＜20×106시，란렬솔、우질배태솔현저저우활력정상조（P＜0．05），대IVF수정솔、충식솔、림상임신솔、조기유산솔무영향（P＞0．05）；당정자정상형태백분솔＜4％시，수정솔현저저우정자형태정상조（P＜0．05），대란렬솔、우질배태솔、림상임신솔、충식솔화조기유산솔무영향（ P＞0．05）。결론정자활력화형태여배태유일정관계，단시부빙정자활력화형태예측배태질량유일정국한성。
Objective To evaluate the effect of the human sperm vitality and morphology on conventional in vitro fertilization Embryo quality .Methods The data including the amount of progressive sperm , the proportion of sperm with normalmorphology .The rates of fertility, cleavage, good quality embryo, implantation, clinical pregnancy and miscarriage of 251 couples receiving IVF treatment were analyzed;the effects of the amount of progressive sperm and morphology on the rates of fertility , good quality embryo , implantation , clinical pregnancy and miscarriage were observed .Results When the amount of progressive sperm was less than 20 × 106, the rate of cleavage and good quality embryo was lower than those in normal vitality groups (P<0.05);when the proportion of sperm with normal morphology was less than 4%, the rate of fertility was lower than those in normal groups (P<0.05).Conclusions Sperm vitality and morphology is related to quality embryo , which relationship is limited .