CAJ | 학술논문

对椎间盘退变机制、BMSCs 生物学特性、支架材料及细胞因子认识的深入，为BMSCs 修复退变的椎间盘组织奠定了基础。研究表明，BMSCs 治疗椎间盘退行性病变具有可行性，临床应用前景广阔。本文就BMSCs 治疗椎间盘退行性病变的研究进展进行综述。
대추간반퇴변궤제、BMSCs 생물학특성、지가재료급세포인자인식적심입，위BMSCs 수복퇴변적추간반조직전정료기출。연구표명，BMSCs 치료추간반퇴행성병변구유가행성，림상응용전경엄활。본문취BMSCs 치료추간반퇴행성병변적연구진전진행종술。
The further understanding of cellular scaffolds, cell factors, intervertebral disc (IVD) cell pathophysiology and BMSCs biology have laid the foundation of cell-based therapies for IVD degeneration. Moreover, a series of animal studies and vitro experiments also confirm the feasibility and effectiveness of cell-based therapies for IVD degeneration. It shows a wide prospect of clinical application in the future. The current research status of BMSCs in IVD tissue engineering was reviewed.