CAJ | 학술논문

目的：调查分析6573例非淋菌性尿道炎（NGU）患者支原体感染情况及对抗菌药物的敏感性，为临床合理用药及流行病学提供依据。方法对6573例NGU患者进行支原体培养及药敏试验，分别对中国籍患者和外籍患者两组进行比较分析。结果在5675例中国籍患者中检出支原体感染2985例（52．6％），其中，解脲支原体（Uu）感染2312例（40．7％）；男性感染率为35．2％，女性感染率为61．4％。898例外籍患者支原体感染440例（49．0％），其中，Uu感染327例（36．4％）；男性感染率为32．2％，女性感染率为59．5％。药敏试验结果显示，中国籍患者Uu感染时敏感率依次为米诺环素（MIN）96．7％、多西环素（DOX）96．2％、交沙霉素（JOS）93．7％、克拉霉素（CLA）89．7％；外籍患者依次为MIN（98．9％）、DOX（98．4％）、JOS（95．8％）、CLA（92．1％）。结论中国籍NGU患者支原体感染率略高于外籍患者，感染类型均以Uu为主；女性感染率均明显高于男性；外籍患者对所试药物敏感性均高于中国籍患者，两组患者对MIN、DOX、JOS及CLA均呈现较强的敏感性。
목적：조사분석6573례비림균성뇨도염（NGU）환자지원체감염정황급대항균약물적민감성，위림상합리용약급류행병학제공의거。방법대6573례NGU환자진행지원체배양급약민시험，분별대중국적환자화외적환자량조진행비교분석。결과재5675례중국적환자중검출지원체감염2985례（52．6％），기중，해뇨지원체（Uu）감염2312례（40．7％）；남성감염솔위35．2％，녀성감염솔위61．4％。898예외적환자지원체감염440례（49．0％），기중，Uu감염327례（36．4％）；남성감염솔위32．2％，녀성감염솔위59．5％。약민시험결과현시，중국적환자Uu감염시민감솔의차위미낙배소（MIN）96．7％、다서배소（DOX）96．2％、교사매소（JOS）93．7％、극랍매소（CLA）89．7％；외적환자의차위MIN（98．9％）、DOX（98．4％）、JOS（95．8％）、CLA（92．1％）。결론중국적NGU환자지원체감염솔략고우외적환자，감염류형균이Uu위주；녀성감염솔균명현고우남성；외적환자대소시약물민감성균고우중국적환자，량조환자대MIN、DOX、JOS급CLA균정현교강적민감성。
Objective To investigate the infection status and drug suscepetibility of mycoplasma from 6 573 patients with non-gonococcal urethritis ,and to provide the scientific bases for the clinical application of antibiotics .Methods Mycoplasma detection kit was used to detect ureaplasma urealyticum (Uu) and mycoplasma hominis(Mh) and the drug susceptibility .All the patients were divided into two groups :Chinese group and foreigner group .Results Among 5 675 Chinese patients ,2 985 patients were infected by mycoplasma(52 .6% ) .The infection rate of Uu was 2 312(40 .7% ) .35 .2% patients were male ,and 61 .4% patients were female .In 898 foreign patients ,440 patients were infected by mycoplasma(49 .0% ) .The infection rate of Uu was 327(36 .4% ) .32 .2% pa-tients were male ,and 59 .5% patients were female .In Chinese patients infected by Uu ,the susceptibility rates to MIN ,DOX ,JOS and CLA were 96 .7% ,96 .2% ,93 .7% ,89 .7% ,respectively .In foreign patients ,the susceptibility rates to MIN ,DOX ,JOS ,and CLA were 98 .9% ,98 .4% ,95 .8% ,92 .1% .Conclusion The mycoplasma infection rate of Chinese patients is higher than foreign patients .In both groups ,Uu infection is the main type .Female patients are more than male patients .The drug sensitivity rate in for-eign group is higher than that in Chinese group .mycoplasma are sensitivity to MIN ,DOX ,JOS .