CAJ | 학술논문

研究了茜素红与阿魏酸哌嗪的显色反应，建立了阿魏酸哌嗪含量测定的分光光度法．在水溶剂中阿魏酸哌嗪与茜素红发生荷移反应生成紫红色的复合物，其最大吸收波长为524 nm ，表观摩尔吸光系数为1．86×103 L ·mol-1·cm -1．阿魏酸哌嗪的浓度在1．60～48．0 mg ·L -1范围内与体系的吸光度呈良好的线性关系，其线性回归方程为 A ＝0．02107＋0．00393c（c ，mg ·L -1，R＝0．9992），方法的检出限为1．19 mg ·L -1．将此新方法应用于阿魏酸哌嗪片中阿魏酸哌嗪含量的测定，回收率在97．5％～100．9％之间．
연구료천소홍여아위산고진적현색반응，건립료아위산고진함량측정적분광광도법．재수용제중아위산고진여천소홍발생하이반응생성자홍색적복합물，기최대흡수파장위524 nm ，표관마이흡광계수위1．86×103 L ·mol-1·cm -1．아위산고진적농도재1．60～48．0 mg ·L -1범위내여체계적흡광도정량호적선성관계，기선성회귀방정위 A ＝0．02107＋0．00393c（c ，mg ·L -1，R＝0．9992），방법적검출한위1．19 mg ·L -1．장차신방법응용우아위산고진편중아위산고진함량적측정，회수솔재97．5％～100．9％지간．
A new method for the determination of piperazine ferulate by spectrophotometry is established using alizarin red as a chromogenic reagent .In water solution ,the charge transfer reaction between piperazine ferulate and alizarin red was investigated and the purple color com-plex was formed .The apparent molar absorptivity of the complex is 1 .86 × 103 L ·mol-1·cm -1 at the maximum absorption wavelength of 524 nm .The Beer's Law is obeyed in the range of 1 . 60 -48 .0 mg ·L -1 of piperazine ferulate .T he linear regression equation of the calibration curve was A = 0 .021 07+0 .003 93 c (c ,mg ·L -1 ) with a correlation coefficient of 0 .999 2 .The de-tection limit was 1 .19 mg ·L -1 .This new method is applied to the determination of piperazine ferulate in tablets with recoveries of 97 .5% -100 .9% .