化学研究
化學研究
화학연구
CHEMICAL RESEARCHES
2013年
5期
509-511
,共3页
傅力明%王茹林%王浩江%王鹏
傅力明%王茹林%王浩江%王鵬
부력명%왕여림%왕호강%왕붕
美洛昔康%磺化杯4芳烃%包合作用%荧光光谱
美洛昔康%磺化杯4芳烴%包閤作用%熒光光譜
미락석강%광화배4방경%포합작용%형광광보
meloxicam%4-sulfocalixarene[4]%inclusion interaction%fluorescence spectrometry
采用荧光光谱研究了不同酸度下美洛昔康(ME)与4-磺化杯[4]芳烃(SCX4)的包合作用。结果表明,在酸性和中性条件下,美洛昔康与4-磺化杯[4]芳烃均形成1∶1的包合物;以包合形成常数为包合物稳定性的量度,不同酸度下形成的包合物的稳定性排序为碱性>中性>酸性。
採用熒光光譜研究瞭不同痠度下美洛昔康(ME)與4-磺化杯[4]芳烴(SCX4)的包閤作用。結果錶明,在痠性和中性條件下,美洛昔康與4-磺化杯[4]芳烴均形成1∶1的包閤物;以包閤形成常數為包閤物穩定性的量度,不同痠度下形成的包閤物的穩定性排序為堿性>中性>痠性。
채용형광광보연구료불동산도하미락석강(ME)여4-광화배[4]방경(SCX4)적포합작용。결과표명,재산성화중성조건하,미락석강여4-광화배[4]방경균형성1∶1적포합물;이포합형성상수위포합물은정성적량도,불동산도하형성적포합물적은정성배서위감성>중성>산성。
The inclusion interaction of meloxicam with 4-sulfocalixarene[4] was investigated by fluorescence spectrometry .Results show that the inclusion interaction between meloxicam and 4-sulfocalixarene[4] leads to inclusion compounds with a stoichiometric ratio of 1∶1 under both acidic and neutral conditions .Besides ,in terms of the inclusion constant between meloxi-cam and 4-sulfocalixarene [4] ,resultant inclusion compounds formed under alkaline ,neutral , and acidic conditions show gradually declined stability .