化学分析计量
化學分析計量
화학분석계량
CHEMICAL ANALYSIS AND METERAGE
2013年
5期
30-32
,共3页
四环素%土霉素%罗红霉素%固相萃取%液质联用
四環素%土黴素%囉紅黴素%固相萃取%液質聯用
사배소%토매소%라홍매소%고상췌취%액질련용
tetracyclin%oxytetracycline%roxithromycin%SPE%UPLC-MS/MS
建立了固相萃取-超高效液相色谱三重四级杆质谱联用法同时测定水中的罗红霉素、四环素和土霉素残留。水样经过固相萃取纯化、富集，液质联用分析，采用甲酸溶液和乙腈作为流动相，在5 min内完成对3种目标化合物的分析，3种目标化合物的方法检出限介于0.08～0.35 ng/L之间，测定结果的相对标准偏差为1.4%~5.6%，空白样品和实际样品的加标回收率分别为82.5%～114%，71.5%～126%。
建立瞭固相萃取-超高效液相色譜三重四級桿質譜聯用法同時測定水中的囉紅黴素、四環素和土黴素殘留。水樣經過固相萃取純化、富集，液質聯用分析，採用甲痠溶液和乙腈作為流動相，在5 min內完成對3種目標化閤物的分析，3種目標化閤物的方法檢齣限介于0.08～0.35 ng/L之間，測定結果的相對標準偏差為1.4%~5.6%，空白樣品和實際樣品的加標迴收率分彆為82.5%～114%，71.5%～126%。
건립료고상췌취-초고효액상색보삼중사급간질보련용법동시측정수중적라홍매소、사배소화토매소잔류。수양경과고상췌취순화、부집，액질련용분석，채용갑산용액화을정작위류동상，재5 min내완성대3충목표화합물적분석，3충목표화합물적방법검출한개우0.08～0.35 ng/L지간，측정결과적상대표준편차위1.4%~5.6%，공백양품화실제양품적가표회수솔분별위82.5%～114%，71.5%～126%。
A rapid analytical method for simultaneous determination of tetracyclin, oxytetracycline and roxithromycin in water sample was developed. Water samples were purified and concentrated by solid phase extraction(SPE), then analyzed by ultra performance liquid chromatography electrospray tandem mass spectrometry(UPLC-MS/MS). Using formic acid and acetonitrile as the mobile phase, the three antibiotics were separated within 5 min. The limit of determination for anlytes were 0.08-0.35 ng/L with the relative standard deviation of 1.4%-5.6%. The recoveries of the antibiotics were in the range of 82.5%-114%for blank and 71.5%-126%for real samples.
