CAJ | 학술논문

目的：探讨术前经肝动脉化疗栓塞术（TACE）对肝细胞肝癌（HCC）肝切除患者生存及预后的影响。方法回顾性分析130例肝癌患者资料，术前选择性经肝动脉化疗栓塞（TACE组）65例，术前未行经肝动脉化疗栓塞（对照组）65例。比较术后1、2、3年复发率及生存率变化，评价可切除肝癌术前选择性经肝动脉化疗栓塞的作用。结果1、3年复发率两组无差异，2年复发率TACE组为31.2%，对照组为59.2%，TACE组明显低于对照组（P＜0.05）；3年生存率TACE组为54.1%，对照组为32.3%，TACE组明显高于对照组（P＜0.05）。结论可切除肝癌术前严格掌握条件选择性TACE可在一定程度上提高手术治疗的效果。
목적：탐토술전경간동맥화료전새술（TACE）대간세포간암（HCC）간절제환자생존급예후적영향。방법회고성분석130례간암환자자료，술전선택성경간동맥화료전새（TACE조）65례，술전미행경간동맥화료전새（대조조）65례。비교술후1、2、3년복발솔급생존솔변화，평개가절제간암술전선택성경간동맥화료전새적작용。결과1、3년복발솔량조무차이，2년복발솔TACE조위31.2%，대조조위59.2%，TACE조명현저우대조조（P＜0.05）；3년생존솔TACE조위54.1%，대조조위32.3%，TACE조명현고우대조조（P＜0.05）。결론가절제간암술전엄격장악조건선택성TACE가재일정정도상제고수술치료적효과。
Objective To explore the effect of preoperative transcatheter arterial chemoembolization(TACE) on life quality and prognosis of patients with hepatocellular carcinoma receiving hepatectomy. Methods Data of 130 patients with hepatic cancer were analyzed retrospectively. 65 patients received preoperative TACE(TACE group), and 65 patients did not receive preoperative TACE(control group). Changes of relapse rate and survival rate in 1, 2, 3 years after the surgery were compared, and the effect of preoperative TACE for resectable hepatic cancer was evaluated. Results There was no difference of 1-year and 3-year relapse rate between the two groups. 2-year relapse rate in the TACE group was 31.2%, significantly lower than that of 59.2%in the control group(P<0.05);3-year survival rate in the TACE group was 54.1%, significantly higher than that of 32.3%in the control group(P<0.05). Conclusion Preoperative elective TACE for resectable hepatic cancer under strict conditions, to some extent, can improve the curative effect of the surgery.