CAJ | 학술논문

目的：探讨自然界各种过敏原与慢性湿疹患者发病的关系，为患者的预防和治疗提供指导依据，并对治疗后的效果进行统计学评价。方法采用深圳雷杜BIotray866全自动过敏原分析仪器对274例慢性湿疹患者进行过敏原的检测，在脱敏治疗后观察疗效，同时设立125例对照湿疹患者，不进行脱敏治疗只进行常规湿疹治疗。结果274例慢性湿疹患者的变应原检测阳性率达79.56%（218例)；在阳性患者过敏原中粉尘螨46例阳性率最高，其次为海鲜类，牛、羊、奶类，有的患者为多种过敏原过敏。对患者进行脱敏治疗后并远离其过敏原，跟踪1年后只有28例（12.84%）复发，相比于对照组72例（57.6%）复发，有明显疗效。结论对于慢性顽固性湿疹患者在诊疗过程中应积极寻找病因，避免在日常生活中接触相应的致病过敏原，能够有效帮助治疗和预防疾病，并明显降低复发率。
목적：탐토자연계각충과민원여만성습진환자발병적관계，위환자적예방화치료제공지도의거，병대치료후적효과진행통계학평개。방법채용심수뢰두BIotray866전자동과민원분석의기대274례만성습진환자진행과민원적검측，재탈민치료후관찰료효，동시설립125례대조습진환자，불진행탈민치료지진행상규습진치료。결과274례만성습진환자적변응원검측양성솔체79.56%（218례)；재양성환자과민원중분진만46례양성솔최고，기차위해선류，우、양、내류，유적환자위다충과민원과민。대환자진행탈민치료후병원리기과민원，근종1년후지유28례（12.84%）복발，상비우대조조72례（57.6%）복발，유명현료효。결론대우만성완고성습진환자재진료과정중응적겁심조병인，피면재일상생활중접촉상응적치병과민원，능구유효방조치료화예방질병，병명현강저복발솔。
Objective To explore the relations between various allergens in nature and the morbidity of chronic eczema so as to provide guidance for prevention and treatment for the patients, and carry out a statistical assessment towards the curative effect after the treatment. Methods Allergens of 274 patients with chronic eczema were tested via BIotray866 Auto Blot Processor produced in Shenzhen Rayto Life and Analytical Sciences Co.,Ltd. The curative effect was observed after desensitization treatment. 125 patients with chronic eczema were selected as a control group, and received regular treatment for eczema instead of the desensitization treatment. Results Positive rate of allergens in 274 patients with chronic eczema reached up to 79.56%(218 patients); among the allergens for patients with positive results, the positive rate of dermatophagoides farina ranked the first with 46 patients, and other allergens were seafood, cow's milk and sheep's milk. Some patients were allergic to multiple allergens. The patients received desensitization treatment and kept away from the allergens, and only 28 patients(12.84%) relapsed in a 1-year follow-up, showing a significantly curative effect compared with 72 relapsed patients(57.6%) in the control group. Conclusion For patients with chronic intractable eczema, causes of disease should be actively traced during diagnosis and treatment, and related allergens should be avoided during their daily life. In such way, diseases can be effectively treated and prevented, and relapse rate can be significantly reduced.