CAJ | 학술논문

目的：探讨颅内动脉瘤介入治疗中丙泊酚全麻诱导靶控注射与人工输注方式的临床价值。方法选取2011~2012年我院颅内动脉瘤介入治疗的患者60例，随机分为两组行不同方式的丙泊酚麻醉诱导，统计两组患者不同麻醉时间的血流动力学指标以及麻醉效果。结果两组患者麻醉诱导时间、苏醒时间无明显差异；相比对照组，观察组丙泊酚用量明显较高，麻醉效果明显较好，诱导期后血压下降明显较少，不良反应发生率明显较低。结论颅内动脉瘤介入治疗中丙泊酚靶控输注相比人工输注具有更好的麻醉效果，血液动力学指标变化较小，安全性更高，适合临床推广。
목적：탐토로내동맥류개입치료중병박분전마유도파공주사여인공수주방식적림상개치。방법선취2011~2012년아원로내동맥류개입치료적환자60례，수궤분위량조행불동방식적병박분마취유도，통계량조환자불동마취시간적혈류동역학지표이급마취효과。결과량조환자마취유도시간、소성시간무명현차이；상비대조조，관찰조병박분용량명현교고，마취효과명현교호，유도기후혈압하강명현교소，불량반응발생솔명현교저。결론로내동맥류개입치료중병박분파공수주상비인공수주구유경호적마취효과，혈액동역학지표변화교소，안전성경고，괄합림상추엄。
Objective To explore the clinical value of target controlled infusion-induced general anesthesia with propofol and manual infusion in interventional treatment of intracranial aneurysm. Methods 60 patients who received interventional treatment of intracranial aneurysm in our hospital from 2011 to 2012 were selected and randomly assigned to two groups which received two different ways of anesthesia induction with propofol. Hemodynamic parameters and anesthetic effects at different time of anesthesia in the two groups were collected. Results Anesthesia induction time and awakening time between the two groups were not significantly different;compared with the control group, the amount of propofol used in the observation group was significantly larger, and the anesthetic effect was obviously better. Fall of blood pressure after the induction was evidently minor and the incidence rate of adverse events was significantly lower. Conclusion In the interventional treatment of intracranial aneurysm, TCI with propofol has better anesthetic effect than manual infusion. It causes minor changes of hemodynamic parameters, which is a safer method and worthy of clinical promotion.