CAJ | 학술논문

目的：研究防茄软膏的制备工艺及其质量控制标准。方法采用了正交试验设计来寻找防茄软膏制备工艺的最佳方案，并进行的主要药效学及毒理学试验。结果对软膏中所用基质的种类、每种基质的用量，油相和水相的比例，调制的湿度及方法等方面，进行了多次试验比较，以研究得到最佳的软膏的调配方法及疗效。结论完成了制备工艺后，对防茄软膏的原料药和成药进行了薄层色谱定性和高效液相色谱定量的研究，采用了薄层色谱法鉴别制剂中的赤芍、桂枝、防己、白芷四味药材，结果表明薄层色谱斑点清晰，特征性强，重现性好，阴性无干扰。
목적：연구방가연고적제비공예급기질량공제표준。방법채용료정교시험설계래심조방가연고제비공예적최가방안，병진행적주요약효학급독이학시험。결과대연고중소용기질적충류、매충기질적용량，유상화수상적비례，조제적습도급방법등방면，진행료다차시험비교，이연구득도최가적연고적조배방법급료효。결론완성료제비공예후，대방가연고적원료약화성약진행료박층색보정성화고효액상색보정량적연구，채용료박층색보법감별제제중적적작、계지、방기、백지사미약재，결과표명박층색보반점청석，특정성강，중현성호，음성무간우。
Objective To study the preparation procedure and quality control standards of Fang Qie Ointment.Methods To find the available proposal by orthogonal test, and primary preview Fang Qie Ointment's toxicology and medical effects.Results After many experiment comparative,the group qualitative beautiful match ratio.The degree and the ways to research the perfect degree and effect of ointment.Conclusion After research for its preparation procedure,we also work out the strictly quality control ways and standards by TLC and HPLC duringthe process,the experiment proved that the stability,recovery. reproducibility and accuracy are satisfactory.