海南医学
海南醫學
해남의학
HAINAN MEDICAL JOURNAL
2014年
15期
2214-2215,2216
,共3页
唐移忠%陈焕仪%江晓丽%谭玉冰
唐移忠%陳煥儀%江曉麗%譚玉冰
당이충%진환의%강효려%담옥빙
乳酸菌阴道胶囊%细菌性阴道病%应用有效性%安全性
乳痠菌陰道膠囊%細菌性陰道病%應用有效性%安全性
유산균음도효낭%세균성음도병%응용유효성%안전성
Lactobacillus vaginal capsules%Bacterial vaginosis%Application effectiveness%Safety
目的：评价乳酸菌阴道胶囊治疗细菌性阴道病的临床疗效及其安全性。方法选取我院2013年5月至2013年12月期间门诊诊治的160例患者，所有患者按随机数表法分为观察组和对照组各80例，观察组采用乳酸菌阴道胶囊治疗，对照组采用阴道放置双唑泰栓，两组患者连续治疗7d为一个疗程，共治疗4个疗程，观察并比较两组患者的治疗效果和复发情况。结果观察组治愈有效率为93.8%，对照组为73.8%，两组比较差异有统计学意义(P<0.05)。治疗1个月后，观察组复发5例(6.25%)，对照组复发13例(16.25%)，两组比较差异无统计学意义(P>0.05)。治疗2个月后，观察组复发11例(13.75%)，对照组复发29例(36.25%)，两组比较差异有统计学意义(P<0.05)。观察组不良反应率为3.75%，对照组不良反应率为20.00%，两组比较差异有显著统计学意义(P<0.01)。结论乳酸菌阴道胶囊能够有效的应用于治疗细菌性阴道病，并且治疗后的不良反应及复发率均较低。
目的：評價乳痠菌陰道膠囊治療細菌性陰道病的臨床療效及其安全性。方法選取我院2013年5月至2013年12月期間門診診治的160例患者，所有患者按隨機數錶法分為觀察組和對照組各80例，觀察組採用乳痠菌陰道膠囊治療，對照組採用陰道放置雙唑泰栓，兩組患者連續治療7d為一箇療程，共治療4箇療程，觀察併比較兩組患者的治療效果和複髮情況。結果觀察組治愈有效率為93.8%，對照組為73.8%，兩組比較差異有統計學意義(P<0.05)。治療1箇月後，觀察組複髮5例(6.25%)，對照組複髮13例(16.25%)，兩組比較差異無統計學意義(P>0.05)。治療2箇月後，觀察組複髮11例(13.75%)，對照組複髮29例(36.25%)，兩組比較差異有統計學意義(P<0.05)。觀察組不良反應率為3.75%，對照組不良反應率為20.00%，兩組比較差異有顯著統計學意義(P<0.01)。結論乳痠菌陰道膠囊能夠有效的應用于治療細菌性陰道病，併且治療後的不良反應及複髮率均較低。
목적：평개유산균음도효낭치료세균성음도병적림상료효급기안전성。방법선취아원2013년5월지2013년12월기간문진진치적160례환자，소유환자안수궤수표법분위관찰조화대조조각80례，관찰조채용유산균음도효낭치료，대조조채용음도방치쌍서태전，량조환자련속치료7d위일개료정，공치료4개료정，관찰병비교량조환자적치료효과화복발정황。결과관찰조치유유효솔위93.8%，대조조위73.8%，량조비교차이유통계학의의(P<0.05)。치료1개월후，관찰조복발5례(6.25%)，대조조복발13례(16.25%)，량조비교차이무통계학의의(P>0.05)。치료2개월후，관찰조복발11례(13.75%)，대조조복발29례(36.25%)，량조비교차이유통계학의의(P<0.05)。관찰조불량반응솔위3.75%，대조조불량반응솔위20.00%，량조비교차이유현저통계학의의(P<0.01)。결론유산균음도효낭능구유효적응용우치료세균성음도병，병차치료후적불량반응급복발솔균교저。
Objective To evaluate the application effectiveness and safety of lactobacillus vaginal capsules in bacterial vaginosis. Methods One hundred and sixty cases of patients with bacterial vaginosis in our clinic be-tween May 2013 to December 2013 were selected and divided into observation group and control group by therapeutic methods. Patients in the observation group were cured by lactobacillus vagina capsule, while those in the control group were treated with metronidazole clotrimazole. All patients were continuously given four courses with 7 days in each course. Then the treatment effect was reviewed. Results The cure effective rate in the observation group was 93.8% and it was 73.8% in the control group. There was a significant difference between the two groups (P<0.05). One month after the treatment, patients in the observation group had a recurrence of 5 cases (6.25%), while there were 5 cases (16.25%) in the control group. There was no significant difference in recurrence rate between these two groups (P>0.05). Two months after treatment, there were 11 cases (13.75%) and 29 cases (36.25%) of the recurrence patients in the observation group and the control group respectively, with a significant difference (P<0.05). The patients with adverse reactions in the observation group was 3 cases (3.25%) and it was 16 cases (20%) in the control group, with a significant difference (P<0.05). Conclusion The lactobacillus vaginal capsules, which had lower recurrence rate and adverse reactions after treatment, showes higher efficiency in the treatment of women bacterial vaginal.
