CAJ | 학술논문

目的：研究女性不孕症患者的促卵泡激素（FSH）、泌乳素（PRL）、雌二醇（E2）、促黄体生成素（LH）等指标特征对于临床诊断价值。方法选取2011年2月至2013年2月在该院治疗的128例不孕症患者为研究对象，根据月经情况分为月经正常组40例和月经紊乱组88例，选取同期健康体检女性100例为对照组。所有研究对象在月经2～3 d抽空腹静脉血5 mL ，分离血清，应用全自动化学发光检测仪进行 FSH、PRL、E2、LH等激素水平进行测定，比较月经正常组、月经紊乱组和对照组患者的FS H、PRL、E2、L H等激素水平。分析FS H、PRL、E2、L H等激素对不孕症的影响。同时随访比较不孕症患者治愈后与对照组FSH、PRL、HL、E2等激素水平情况。结果月经紊乱组患者的FS H、PRL、L H激素水平明显高于对照组，差异具有统计学意义（ P＜0．05）；E2激素水平明显低于对照组，差异具有统计学意义（P＜0．05）。月经正常组患者的 FSH、PRL、LH、E2等激素水平与对照组比较，差异无统计学意义（ P＞0．05）。不孕症患者治愈后与对照组比较，两组的 FS H、PRL、E2、L H等激素水平差异无统计学意义。结论女性不孕症患者的FS H、PRL等激素的测定对临床上诊断不孕症具有重要意义。同时也是监测不孕症治疗效果的一种重要方法。
목적：연구녀성불잉증환자적촉란포격소（FSH）、비유소（PRL）、자이순（E2）、촉황체생성소（LH）등지표특정대우림상진단개치。방법선취2011년2월지2013년2월재해원치료적128례불잉증환자위연구대상，근거월경정황분위월경정상조40례화월경문란조88례，선취동기건강체검녀성100례위대조조。소유연구대상재월경2～3 d추공복정맥혈5 mL ，분리혈청，응용전자동화학발광검측의진행 FSH、PRL、E2、LH등격소수평진행측정，비교월경정상조、월경문란조화대조조환자적FS H、PRL、E2、L H등격소수평。분석FS H、PRL、E2、L H등격소대불잉증적영향。동시수방비교불잉증환자치유후여대조조FSH、PRL、HL、E2등격소수평정황。결과월경문란조환자적FS H、PRL、L H격소수평명현고우대조조，차이구유통계학의의（ P＜0．05）；E2격소수평명현저우대조조，차이구유통계학의의（P＜0．05）。월경정상조환자적 FSH、PRL、LH、E2등격소수평여대조조비교，차이무통계학의의（ P＞0．05）。불잉증환자치유후여대조조비교，량조적 FS H、PRL、E2、L H등격소수평차이무통계학의의。결론녀성불잉증환자적FS H、PRL등격소적측정대림상상진단불잉증구유중요의의。동시야시감측불잉증치료효과적일충중요방법。
Objective To study the FSH (follicle stimulating hormone) ,PRL (prolactin) ,E2 (estradiol) ,LH (luteinizing hormone ) and other hormone characteristics and clinical diagnostic value of female infertility patients . Methods 128 cases of infertility patients selected form February 2011-February 2013 in our hospital for the study , divided into normal group with 40 cases and menstrual disorders group roith 88 cases ,according to the menstrual pe-riod and another 100 cases of physical health examination women were selected as the control group .All the research objects were taken abdominal venous blood 5 mL 2-3 days in menstruation ,separation of serum ,application of full automatic chemiluminescence detector to determine FSH ,LH ,PRL ,E2 ,hormone levels compared .Compare FSH , PRL ,E2 ,LH hormone levels ,etc in normal menstruation ,menstrual disorders group and control group .Analysis of the influence of FSH ,LH ,PRL ,E2 hormones on infertility .Meanwhile cure infertility patients were followed up after comparison with the control group ,FSH ,PRL ,HL ,E2 hormone levels and other conditions .Results After disorder group of patients FSH ,PRL ,LH hormone levels were significantly higher ,the difference was statistically significant (P<0 .05);E2 hormone levels were significantly lower than the control group ,the difference was statistically signifi-cant (P<0 .05) .Group of patients with normal menstrual FSH ,PRL ,LH ,E2 and other hormone levels compared with control group ,the difference was not statistically significant (P>0 .05) .After cure infertility compared with the control group ,no difference was observed in FSH ,PRL ,E2 ,LH and other hormone levels .Conclusion The determi-nation of FSH ,PRL and other characteristics of female infertility patients had important clinical value ,with could provide significant basis for the clinical diagnosis and treatment of infertility patients .