检验医学与临床
檢驗醫學與臨床
검험의학여림상
JOURNAL OF LABORATORY MEDICINE AND CLINICAL SCIENCES
2014年
15期
2133-2134
,共2页
网织红细胞相关参数%血液分析仪%溶血性贫血%缺铁性贫血%再生障碍性贫血
網織紅細胞相關參數%血液分析儀%溶血性貧血%缺鐵性貧血%再生障礙性貧血
망직홍세포상관삼수%혈액분석의%용혈성빈혈%결철성빈혈%재생장애성빈혈
reticulocyte-related parameter%blood analyzer%hemolytic anemia%iron-deficiency anemia%aplastic anemia
目的：探讨网织红细胞（RET ）相关参数检测在贫血性疾病中的临床意义。方法应用Sysmex XE-5000全自动血液分析仪对患者的 RET 百分比（RET％）、RET 绝对值（RET ＃）、高荧光强度网织红细胞百分比（H FR％）、中荧光强度网织红细胞百分比（M FR％）、低荧光强度网织红细胞百分比（L FR％）以及未成熟网织红细胞比率（IRF）进行检测，并与对照组进行比较分析。结果溶血性贫血患者LFR％降低，RET％、RET ＃、HFR％、M FR％以及IRF均比对照组明显升高，差异有统计学意义（ P＜0．01）；再生障碍性贫血患者 RET％、RET ＃、HFR％、MFR％、LFR％以及 IRF明显降低，差异有统计学意义（P＜0．01）；缺铁性贫血患者 RET％、RET ＃、H FR％、M FR％、L FR％以及IRF比对照组稍增高，但差异无统计学意义。结论网织红细胞相关参数检测可以更准确反映网织红细胞的成熟状态，从而判断骨髓的造血功能，对不同类型的贫血性疾病的诊断、治疗具有重要参考价值。
目的：探討網織紅細胞（RET ）相關參數檢測在貧血性疾病中的臨床意義。方法應用Sysmex XE-5000全自動血液分析儀對患者的 RET 百分比（RET％）、RET 絕對值（RET ＃）、高熒光彊度網織紅細胞百分比（H FR％）、中熒光彊度網織紅細胞百分比（M FR％）、低熒光彊度網織紅細胞百分比（L FR％）以及未成熟網織紅細胞比率（IRF）進行檢測，併與對照組進行比較分析。結果溶血性貧血患者LFR％降低，RET％、RET ＃、HFR％、M FR％以及IRF均比對照組明顯升高，差異有統計學意義（ P＜0．01）；再生障礙性貧血患者 RET％、RET ＃、HFR％、MFR％、LFR％以及 IRF明顯降低，差異有統計學意義（P＜0．01）；缺鐵性貧血患者 RET％、RET ＃、H FR％、M FR％、L FR％以及IRF比對照組稍增高，但差異無統計學意義。結論網織紅細胞相關參數檢測可以更準確反映網織紅細胞的成熟狀態，從而判斷骨髓的造血功能，對不同類型的貧血性疾病的診斷、治療具有重要參攷價值。
목적：탐토망직홍세포（RET ）상관삼수검측재빈혈성질병중적림상의의。방법응용Sysmex XE-5000전자동혈액분석의대환자적 RET 백분비（RET％）、RET 절대치（RET ＃）、고형광강도망직홍세포백분비（H FR％）、중형광강도망직홍세포백분비（M FR％）、저형광강도망직홍세포백분비（L FR％）이급미성숙망직홍세포비솔（IRF）진행검측，병여대조조진행비교분석。결과용혈성빈혈환자LFR％강저，RET％、RET ＃、HFR％、M FR％이급IRF균비대조조명현승고，차이유통계학의의（ P＜0．01）；재생장애성빈혈환자 RET％、RET ＃、HFR％、MFR％、LFR％이급 IRF명현강저，차이유통계학의의（P＜0．01）；결철성빈혈환자 RET％、RET ＃、H FR％、M FR％、L FR％이급IRF비대조조초증고，단차이무통계학의의。결론망직홍세포상관삼수검측가이경준학반영망직홍세포적성숙상태，종이판단골수적조혈공능，대불동류형적빈혈성질병적진단、치료구유중요삼고개치。
Objective To explore the clinical significance of reticulocyte (RET )-related parameters determina-tion in anemia diagnosis .Methods Reticulocyte percentage (RET% ) ,RET count (RET#) ,percent of high fluores-cent reticulocyte (LFR% ) ,percent of middle fluorescent reticulocyte (MFR% ) ,percent of low fluorescent reticulo-cyte (HFR% ) ,and immature RET fraction (IRF) of patients were determined by Sysmex XE-5000 automated blood analyzer and compared with the control group .Results LFR% of patients suffering from hemolytic anemia decrea-ses ,RET% ,RET # ,HFR% ,MFR% and IRF of patients suffering hemolytic anemia were obviously higher than those of normal control group and the difference is quite significant (P< 0 .01);while RET% ,RET # ,HFR% , MFR% ,LFR% and IRF of patients with aplastic anemia were significantly reduced (P< 0 .01);RET% ,RET # , HFR% ,MFR% ,LFR% and IRF of patients suffering iron-deficiency anemia were slightly higher than those of nor-mal control group ,but there were no significant differences among them .Conclusion RET-related parameters are a-ble to reflect the mature of reticulocyte more accurately ,so it can evaluate the hematopoiesis of the bone marrow and it present an important value in the diagnosis and treatment of different types of anemia .
