中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
20期
106-108
,共3页
生殖道炎症%抗精子抗体%免疫性不孕
生殖道炎癥%抗精子抗體%免疫性不孕
생식도염증%항정자항체%면역성불잉
Reproductive tract inflammation%Anti-sperm antibodies%Immune infertility
目的：探讨生殖道炎症与抗精子免疫性不孕的相关性及比较分析中西医不同疗法治疗抗精子免疫性不孕的疗效。方法：从2011年1月-2013年12月本院收治的320名不孕患者中筛选出合格受试者88例，30例采用西药治疗；28例分为阴虚血瘀组、30例湿热蕴积组，分别采用不同中药方剂治疗。结果：320例不孕患者中，合并生殖道炎症者88例，AsAb阳性率54.55%；非炎症者232例，AsAb阳性率29.74%，合并生殖道炎症与非炎症者比较有统计学差异（P<0.05）。3种不同疗法对不孕患者均有显著疗效，三组之间的总有效率差异无统计学意义（P>0.05）。中西医疗法均能在显著降低宫颈黏液IL-2表达量、UU、CT阳性率的同时，显著降低血清抗精子抗体的表达（P<0.05）。结论：中西医疗法均能降低炎症指标水平，起到清除或抑制AsAb产生的作用，从而达到有效治疗炎症性抗精子免疫性不孕的效果。
目的：探討生殖道炎癥與抗精子免疫性不孕的相關性及比較分析中西醫不同療法治療抗精子免疫性不孕的療效。方法：從2011年1月-2013年12月本院收治的320名不孕患者中篩選齣閤格受試者88例，30例採用西藥治療；28例分為陰虛血瘀組、30例濕熱蘊積組，分彆採用不同中藥方劑治療。結果：320例不孕患者中，閤併生殖道炎癥者88例，AsAb暘性率54.55%；非炎癥者232例，AsAb暘性率29.74%，閤併生殖道炎癥與非炎癥者比較有統計學差異（P<0.05）。3種不同療法對不孕患者均有顯著療效，三組之間的總有效率差異無統計學意義（P>0.05）。中西醫療法均能在顯著降低宮頸黏液IL-2錶達量、UU、CT暘性率的同時，顯著降低血清抗精子抗體的錶達（P<0.05）。結論：中西醫療法均能降低炎癥指標水平，起到清除或抑製AsAb產生的作用，從而達到有效治療炎癥性抗精子免疫性不孕的效果。
목적：탐토생식도염증여항정자면역성불잉적상관성급비교분석중서의불동요법치료항정자면역성불잉적료효。방법：종2011년1월-2013년12월본원수치적320명불잉환자중사선출합격수시자88례，30례채용서약치료；28례분위음허혈어조、30례습열온적조，분별채용불동중약방제치료。결과：320례불잉환자중，합병생식도염증자88례，AsAb양성솔54.55%；비염증자232례，AsAb양성솔29.74%，합병생식도염증여비염증자비교유통계학차이（P<0.05）。3충불동요법대불잉환자균유현저료효，삼조지간적총유효솔차이무통계학의의（P>0.05）。중서의요법균능재현저강저궁경점액IL-2표체량、UU、CT양성솔적동시，현저강저혈청항정자항체적표체（P<0.05）。결론：중서의요법균능강저염증지표수평，기도청제혹억제AsAb산생적작용，종이체도유효치료염증성항정자면역성불잉적효과。
To investigate correlation of the reproductive tract inflammation and anti-sperm immune infertility,efficacy of comparative different TCM therapy for anti-sperm immune infertility. Method:88 patients with infertile were screened in 300 cases from January 2012 to December 2013 in our hospital,30 cases were treated by western medicine;28 cases in yin and blood stasis group,30 cases in heat simmers groups were respectively applicated different prescription medicine treatment. Result:AsAb positive rate in 88 cases with genital tract inflammation and 232,with non-inflammatory were Respectively 54.55%;and 29.74%from 320 patients,with infertility,which were significantly different (P<0.05).Three kinds of different treatments had a significant effect on infertility patients,there was no significant difference in efficiency(P>0.05)between the three groups. TCM therapy could significantly reduce cervical mucus expression of IL-2,UU,CT-positive rate,while significantly reducing the expression of anti-sperm antibodies in serum (P<0.05). Conclusion:TCM therapy can reduce the level of inflammatory markers,remove or inhibit AsAb produced, so as to achieve effects of treating in anti-sperm immune infertility with flammatory.
