中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
21期
86-88,89
,共4页
急性脑梗死%血清Hcy%hs-CRP%血脂%相关性
急性腦梗死%血清Hcy%hs-CRP%血脂%相關性
급성뇌경사%혈청Hcy%hs-CRP%혈지%상관성
Acute cerebral infarction%Hcy%hs-CRP%Lipids%Correlation
目的：分析不同年龄段急性脑梗死患者血清Hcy、hs-CRP、血脂水平表达及意义。方法：选取2010年4月-2013年5月本院急诊收治的270例急性脑梗死患者作为研究对象，根据年龄将所有患者分为青年组40例、中年组105例、老年组125例，另选取健康对照组50例，检测hs-CRP、血清Hcy和血脂水平，分析其相关性。结果：中年组与老年组Hcy、hs-CRP、TC、HDL-C、LDL-C，青年组Hcy、hs-CRP、HDL-C与对照组水平相比，差异均有统计学意义（P<0.01）；青中老年组三组中Hcy、hs-CRP、HDL-C检出率均较高，中老年组的LDL-C检出率较高，与其他两组比较差异均有统计学意义（P<0.01）；不同年龄段急性脑梗死患者间TG、TC、HDL-C、LDL-C呈正相关，HDL-C与hs-CRP呈负相关，hs-CRP与血清Hcy之间未见明显相关性。结论：高血清Hcy是临床急性脑梗死患者的典型独立危险因素，可将其作为临床重要参考指标监测患者病情，辅助临床诊疗。
目的：分析不同年齡段急性腦梗死患者血清Hcy、hs-CRP、血脂水平錶達及意義。方法：選取2010年4月-2013年5月本院急診收治的270例急性腦梗死患者作為研究對象，根據年齡將所有患者分為青年組40例、中年組105例、老年組125例，另選取健康對照組50例，檢測hs-CRP、血清Hcy和血脂水平，分析其相關性。結果：中年組與老年組Hcy、hs-CRP、TC、HDL-C、LDL-C，青年組Hcy、hs-CRP、HDL-C與對照組水平相比，差異均有統計學意義（P<0.01）；青中老年組三組中Hcy、hs-CRP、HDL-C檢齣率均較高，中老年組的LDL-C檢齣率較高，與其他兩組比較差異均有統計學意義（P<0.01）；不同年齡段急性腦梗死患者間TG、TC、HDL-C、LDL-C呈正相關，HDL-C與hs-CRP呈負相關，hs-CRP與血清Hcy之間未見明顯相關性。結論：高血清Hcy是臨床急性腦梗死患者的典型獨立危險因素，可將其作為臨床重要參攷指標鑑測患者病情，輔助臨床診療。
목적：분석불동년령단급성뇌경사환자혈청Hcy、hs-CRP、혈지수평표체급의의。방법：선취2010년4월-2013년5월본원급진수치적270례급성뇌경사환자작위연구대상，근거년령장소유환자분위청년조40례、중년조105례、노년조125례，령선취건강대조조50례，검측hs-CRP、혈청Hcy화혈지수평，분석기상관성。결과：중년조여노년조Hcy、hs-CRP、TC、HDL-C、LDL-C，청년조Hcy、hs-CRP、HDL-C여대조조수평상비，차이균유통계학의의（P<0.01）；청중노년조삼조중Hcy、hs-CRP、HDL-C검출솔균교고，중노년조적LDL-C검출솔교고，여기타량조비교차이균유통계학의의（P<0.01）；불동년령단급성뇌경사환자간TG、TC、HDL-C、LDL-C정정상관，HDL-C여hs-CRP정부상관，hs-CRP여혈청Hcy지간미견명현상관성。결론：고혈청Hcy시림상급성뇌경사환자적전형독립위험인소，가장기작위림상중요삼고지표감측환자병정，보조림상진료。
To analyze the expression and significance of Hcy,hs-CRP,blood lipid levels in different age of acute cerebral infarction.Method:270 patients with acute cerebral infarction from April 2010 to May 2013 in our hospital were selected,they were divided of the young group for 40 cases,the middle-aged group for 105 cases, the elderly group for 125 cases according to age.And 50 healthy subjects were selected as the healthy control group,the Hcy,hs-CRP,blood lipid levels were detected,and analyzed the correlation.Result:The middle-aged group compared with elderly group in Hcy,hs-CRP,TC,HDL-C,LDL-C,and the young group compared with the healthy control group in Hcy,hs-CRP,HDL-C,the differences were statistically significant(P<0.01).The Hcy,hs-CRP,HDL-C positive rate in the three groups were significantly higher,LDL-C detection rate in the elderly group was the highest, the differences were statistically significant(P<0.01).Different age patients with acute cerebral infarction between TG,TC,HDL-C,LDL-C were positively correlated,negatively related to HDL-C and hs-CRP,between hs-CRP and Hcy in serum had no obvious correlation.Conclusion:High Hcy is a typical independent risk factors of patients with acute cerebral infarction,can be used as an important reference index for monitoring clinical patients,auxiliary clinical diagnosis.
