中国医学创新
中國醫學創新
중국의학창신
MEDICAL INNOVATION OF CHINA
2014年
21期
60-61,62
,共3页
抑郁症%用药依从性%药学干预
抑鬱癥%用藥依從性%藥學榦預
억욱증%용약의종성%약학간예
Depression%Drug compliance%Pharmaceutical intervention
目的：观察临床过程中药学干预对抑郁症患者服药依从性和疗效的影响。方法：将300例抑郁症患者按随机数字表分为药学干预组（药物治疗+药学干预）和对照组（药物治疗）各150例，对比两组患者初诊时、复诊时、复诊后半年和1年时服药依从性及复诊半年和1年时疾病复发率；并对比不同学历、年龄、性别的患者服药依从性。结果：初诊时两组的服药依从性比较差异无统计学意义（P>0.05），复诊、复诊后半年和1年时药学干预组服药依从性显著高于对照组（P<0.05）；同时药学干预组疾病复发率显著低于对照组（P<0.05）；药学干预组不同学历、年龄、性别患者服药依从性差异无统计学意义（P>0.05）。结论：药学干预可以有效改善抑郁症患者的服药依从性，降低疾病复发率，提高治疗效果。
目的：觀察臨床過程中藥學榦預對抑鬱癥患者服藥依從性和療效的影響。方法：將300例抑鬱癥患者按隨機數字錶分為藥學榦預組（藥物治療+藥學榦預）和對照組（藥物治療）各150例，對比兩組患者初診時、複診時、複診後半年和1年時服藥依從性及複診半年和1年時疾病複髮率；併對比不同學歷、年齡、性彆的患者服藥依從性。結果：初診時兩組的服藥依從性比較差異無統計學意義（P>0.05），複診、複診後半年和1年時藥學榦預組服藥依從性顯著高于對照組（P<0.05）；同時藥學榦預組疾病複髮率顯著低于對照組（P<0.05）；藥學榦預組不同學歷、年齡、性彆患者服藥依從性差異無統計學意義（P>0.05）。結論：藥學榦預可以有效改善抑鬱癥患者的服藥依從性，降低疾病複髮率，提高治療效果。
목적：관찰림상과정중약학간예대억욱증환자복약의종성화료효적영향。방법：장300례억욱증환자안수궤수자표분위약학간예조（약물치료+약학간예）화대조조（약물치료）각150례，대비량조환자초진시、복진시、복진후반년화1년시복약의종성급복진반년화1년시질병복발솔；병대비불동학력、년령、성별적환자복약의종성。결과：초진시량조적복약의종성비교차이무통계학의의（P>0.05），복진、복진후반년화1년시약학간예조복약의종성현저고우대조조（P<0.05）；동시약학간예조질병복발솔현저저우대조조（P<0.05）；약학간예조불동학력、년령、성별환자복약의종성차이무통계학의의（P>0.05）。결론：약학간예가이유효개선억욱증환자적복약의종성，강저질병복발솔，제고치료효과。
To explore the drug compliance effect of pharmaceutical intervention in the treatment of patients with depression.Method:300 patients with depression were randomly divided into the pharmaceutical intervention group(n=150)and the control group(n=150). The pharmaceutical intervention group was treated with antipsychotics and pharmaceutical intervention,and the control group was treated with antipsychotics only. Then the drug therapy compliance were contrasted before treated and discharge from hospital in half a year and 1 year between the two groups. The drug therapy compliance were also contrasted between patients with different educational history,different age and different gender. Result:There was no significantly difference in the drug therapy compliance before treatment of the two groups(P>0.05). But the pharmaceutical intervention group was significantly higher than control group half and one year after the return visit(P<0.05). And the recurrence rate of the disease of the pharmaceutical intervention group was significantly lower than control group(P<0.05). But no significantly difference in the drug therapy compliance between different educational history,different age and different gender(P>0.05).Conclusion:Pharmaceutical intervention can effectively improve the drug therapy compliance,reduce the relapse rate of the disease,and improve the therapeutic effects.
