中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2014年
22期
48-49
,共2页
前降钙素%C反应蛋白%新生儿败血症
前降鈣素%C反應蛋白%新生兒敗血癥
전강개소%C반응단백%신생인패혈증
Procalcitonin%C-reactive protein%Neonatal sepsis
目的：探讨前降钙素(PCT)、C反应蛋白(CRP)测定在新生儿败血症诊断疗效评价中的价值。方法：选择60例新生儿败血症患儿为观察组，选择60同期在笔者所在医院产科分娩的足月健康新生儿为对照组，分别对两组新生儿测定血清PCT及CRP含量并比较，观察组治疗1周后检测血清PCT及CRP含量，比较治疗前后血清PCT及CRP含量的变化。结果：观察组新生儿PCT(8.01±4.02)ng/L、CRP(23.16±3.78)mg/L显著高于对照组(P<0.01)；观察组治疗1周后PCT(1.90±0.25)ng/L、CRP(4.08±1.09)mg/L显著低于治疗前(P<0.01)。结论：新生儿败血症前降钙素及C反应蛋白含量均显著升高，治疗后显著降低，两者测定有助于新生儿败血症的确诊及疗效评价。
目的：探討前降鈣素(PCT)、C反應蛋白(CRP)測定在新生兒敗血癥診斷療效評價中的價值。方法：選擇60例新生兒敗血癥患兒為觀察組，選擇60同期在筆者所在醫院產科分娩的足月健康新生兒為對照組，分彆對兩組新生兒測定血清PCT及CRP含量併比較，觀察組治療1週後檢測血清PCT及CRP含量，比較治療前後血清PCT及CRP含量的變化。結果：觀察組新生兒PCT(8.01±4.02)ng/L、CRP(23.16±3.78)mg/L顯著高于對照組(P<0.01)；觀察組治療1週後PCT(1.90±0.25)ng/L、CRP(4.08±1.09)mg/L顯著低于治療前(P<0.01)。結論：新生兒敗血癥前降鈣素及C反應蛋白含量均顯著升高，治療後顯著降低，兩者測定有助于新生兒敗血癥的確診及療效評價。
목적：탐토전강개소(PCT)、C반응단백(CRP)측정재신생인패혈증진단료효평개중적개치。방법：선택60례신생인패혈증환인위관찰조，선택60동기재필자소재의원산과분면적족월건강신생인위대조조，분별대량조신생인측정혈청PCT급CRP함량병비교，관찰조치료1주후검측혈청PCT급CRP함량，비교치료전후혈청PCT급CRP함량적변화。결과：관찰조신생인PCT(8.01±4.02)ng/L、CRP(23.16±3.78)mg/L현저고우대조조(P<0.01)；관찰조치료1주후PCT(1.90±0.25)ng/L、CRP(4.08±1.09)mg/L현저저우치료전(P<0.01)。결론：신생인패혈증전강개소급C반응단백함량균현저승고，치료후현저강저，량자측정유조우신생인패혈증적학진급료효평개。
Objective:To investigate the value of procalcitonin(PCT),C -reactive protein (CRP) in the diagnosis and treatment of neonatal sepsis. Method:60 cases of neonatal sepsis were as observation group,60 full-term healthy newborns at the same period in our hospital were choosed as control group, respectively,neonatal serum PCT and CRP level was detected and compared in the two groups,and after treating one week in the observation group,serum PCT and CRP level was detected,serum level of PCT and CRP was compared before and after treatment.Result:The level of PCT was (8.01±4.02)ng/L,the level of CRP was (23.16±3.78)mg/L,they were significantly higher in the observation group than those in the control group(P<0.01).After treating one week in the observation group,the level of PCT was (1.90±0.25)ng/L,the level of CRP was (4.08±1.09)mg/L,they were significantly lower than before treatment(P<0.01). Conclusion:The level of procalcitonin and C-reactive protein in neonatal sepsis are significantly increased,and decreased significantly after treatment,they can contribute to diagnosis and treatment evaluation of neonatal sepsis .
