中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2014年
22期
1-2,3
,共3页
视网膜分支静脉阻塞%黄斑水肿%曲安奈德%玻璃体腔注射%激光光凝
視網膜分支靜脈阻塞%黃斑水腫%麯安奈德%玻璃體腔註射%激光光凝
시망막분지정맥조새%황반수종%곡안내덕%파리체강주사%격광광응
Branch retinal vein occlusion%Macular edema%Triamcinolone acetonide%Intravitrcous injection%Laser photocoagulation
目的：评价视网膜激光光凝联合玻璃体腔曲安奈德注射(IVTA)治疗视网膜分支静脉阻塞(BRVO)性黄斑水肿(ME)的疗效和安全性。方法：52例52眼BRVO性ME患者随机分为两组，联合组26例26眼IVTA(4 mg/0.1 ml)后1周行激光光凝，激光组26例26眼仅行激光光凝。随访6个月观察视力、眼底、黄斑水肿及并发症等。结果：治疗后1、3、6个月随访，两组患者治疗前后最佳矫正视力均提高，差异有统计学意义(P<0.05)，联合组视力优于激光组，差异有统计学意义(P<0.05)，黄斑中心凹厚度联合组低于激光组(P<0.05)，激光组并发症低于联合组(P<0.05)。结论：IVTA联合激光光凝是治疗BRVO性ME的有效方法，尤其是对于光凝治疗无效患者，但其长期疗效和安全性还需进一步观察。
目的：評價視網膜激光光凝聯閤玻璃體腔麯安奈德註射(IVTA)治療視網膜分支靜脈阻塞(BRVO)性黃斑水腫(ME)的療效和安全性。方法：52例52眼BRVO性ME患者隨機分為兩組，聯閤組26例26眼IVTA(4 mg/0.1 ml)後1週行激光光凝，激光組26例26眼僅行激光光凝。隨訪6箇月觀察視力、眼底、黃斑水腫及併髮癥等。結果：治療後1、3、6箇月隨訪，兩組患者治療前後最佳矯正視力均提高，差異有統計學意義(P<0.05)，聯閤組視力優于激光組，差異有統計學意義(P<0.05)，黃斑中心凹厚度聯閤組低于激光組(P<0.05)，激光組併髮癥低于聯閤組(P<0.05)。結論：IVTA聯閤激光光凝是治療BRVO性ME的有效方法，尤其是對于光凝治療無效患者，但其長期療效和安全性還需進一步觀察。
목적：평개시망막격광광응연합파리체강곡안내덕주사(IVTA)치료시망막분지정맥조새(BRVO)성황반수종(ME)적료효화안전성。방법：52례52안BRVO성ME환자수궤분위량조，연합조26례26안IVTA(4 mg/0.1 ml)후1주행격광광응，격광조26례26안부행격광광응。수방6개월관찰시력、안저、황반수종급병발증등。결과：치료후1、3、6개월수방，량조환자치료전후최가교정시력균제고，차이유통계학의의(P<0.05)，연합조시력우우격광조，차이유통계학의의(P<0.05)，황반중심요후도연합조저우격광조(P<0.05)，격광조병발증저우연합조(P<0.05)。결론：IVTA연합격광광응시치료BRVO성ME적유효방법，우기시대우광응치료무효환자，단기장기료효화안전성환수진일보관찰。
Objective:To evaluate the efficacy and safety of treatment combined intravitreous injection Triamcinolone Acetonide(IVTA) with laser photocoagulation(LP) for branch retinal vein occlusion(BRVO) with maeular edema(ME).Method:Fifty-two patients(fifty-two eyes) with BRVO with ME were randomly divided into two groups,combination group:twenty-six eyes were treated with IVTA(4 mg/0.1 ml),and LP was used to treat all of the patients after one week.Laser group:twenty-six eyes were treated with LG.Best-corrected visual acuity(BCVA),central macular thinckness(CMT) and the incidence of complications were observed after the treatment.Result:For the different follow-up times at one month,three months,six months,BCVA and CMT of all patients improved after treatment,there were statistically significant differences between before treatment and after treatment in BCVA(P<0.05).Combination group was better than that of laser group(P>0.05).The CMT lowered in the combination group after treatment(P<0.05).The difference in the incidence of complications between the two groups showed a statistically significant difference(P<0.05).Conclusion:IVTA combined with LP can be an effective method in the treatment of DME,especially for patients which LP treatment is invalid,but its long-term efficacy and safety still need further observation.
