CAJ | 학술논문

目的：观察芪苈强心胶囊治疗慢性充血性心力衰竭的临床疗效。方法将慢性心力衰竭患者120例随机分为治疗组和对照组各60例，对照组给予西医常规治疗，治疗组在此基础上加用芪苈强心胶囊，4粒/次，3次/d，疗程4个月。观察两组患者治疗前后的心力衰竭症状体征，左室射血分数(EF)，N末端脑钠肽前体(NTpro-BNP)、6min步行试验(6MWT)。结果治疗组总有效率(98.3%)显著高于对照组(78.3%)，P<0.05。治疗后两组患者LVEF、6MWT、NTpro-BNP均明显提高(P<0.05)。结论芪苈强心胶囊联合常规西医法治疗慢性心力衰竭疗效优于单纯西医常规治疗法，用药安全可靠，值得临床推广应用。
목적：관찰기력강심효낭치료만성충혈성심력쇠갈적림상료효。방법장만성심력쇠갈환자120례수궤분위치료조화대조조각60례，대조조급여서의상규치료，치료조재차기출상가용기력강심효낭，4립/차，3차/d，료정4개월。관찰량조환자치료전후적심력쇠갈증상체정，좌실사혈분수(EF)，N말단뇌납태전체(NTpro-BNP)、6min보행시험(6MWT)。결과치료조총유효솔(98.3%)현저고우대조조(78.3%)，P<0.05。치료후량조환자LVEF、6MWT、NTpro-BNP균명현제고(P<0.05)。결론기력강심효낭연합상규서의법치료만성심력쇠갈료효우우단순서의상규치요법，용약안전가고，치득림상추엄응용。
Objective To observe the clinical ef icacy of Qiliqiangxin capsule in the treatment of CHF.Methods 120 patients with CHF were randomly divided into treatment group with 60 cases and control group with 60 cases. Control group received conventional western medicine therapy, and based on this, the treatment group added in Qiliqiangxin capsule,4 granules every time, 3 times a day, treatment of 4 months. The signs of heart failure symptoms in pre-therapy and post-therapy of two groups, EF, NTpro-BNP and 6MWT can be observed. Results The total ef iciency in treatment group(98.3%) was higher than that in control group(78.3%,P<0.05). The patients'LVEF, 6MWT, NTpro-BNP after treatment was significantly improved ( P<0.05). Conclusion The effect of Qiliqiangxin capsule combined with conventional western medicine in the treatment of CHF is better than that of conventional western medicine, and it is safe and reliable. It is worthy of clinical application.