临床合理用药杂志
臨床閤理用藥雜誌
림상합리용약잡지
CHINESE JOURNAL OF CLINICAL RATIONAL DRUG USE
2014年
22期
1-2
,共2页
美托洛尔%比索洛尔%高血压
美託洛爾%比索洛爾%高血壓
미탁락이%비색락이%고혈압
Metoprolol%Bisoprolol%Hypertension
目的：对比观察美托洛尔与比索洛尔治疗高血压的临床疗效。方法将200例高血压患者随机分为美托洛尔组和比索洛尔组各100例，观察2组临床疗效，并在治疗前后进行偶测血压和24h 动态血压监测。结果2组临床疗效差异无统计学意义（P ＞0．05）。2组治疗前 SBP、DBP 水平差异无统计学意义（P ＞0．05）。治疗后2组SBP、DBP 水平均低于治疗前，且比索洛尔组降低幅度大于美托洛尔组，差异均有统计学意义（P ＜0．05）。结论比索洛尔对24h 血压的控制优于美托洛尔，值得临床推广应用。
目的：對比觀察美託洛爾與比索洛爾治療高血壓的臨床療效。方法將200例高血壓患者隨機分為美託洛爾組和比索洛爾組各100例，觀察2組臨床療效，併在治療前後進行偶測血壓和24h 動態血壓鑑測。結果2組臨床療效差異無統計學意義（P ＞0．05）。2組治療前 SBP、DBP 水平差異無統計學意義（P ＞0．05）。治療後2組SBP、DBP 水平均低于治療前，且比索洛爾組降低幅度大于美託洛爾組，差異均有統計學意義（P ＜0．05）。結論比索洛爾對24h 血壓的控製優于美託洛爾，值得臨床推廣應用。
목적：대비관찰미탁락이여비색락이치료고혈압적림상료효。방법장200례고혈압환자수궤분위미탁락이조화비색락이조각100례，관찰2조림상료효，병재치료전후진행우측혈압화24h 동태혈압감측。결과2조림상료효차이무통계학의의（P ＞0．05）。2조치료전 SBP、DBP 수평차이무통계학의의（P ＞0．05）。치료후2조SBP、DBP 수평균저우치료전，차비색락이조강저폭도대우미탁락이조，차이균유통계학의의（P ＜0．05）。결론비색락이대24h 혈압적공제우우미탁락이，치득림상추엄응용。
Objective To comparative observation the clinical effect of metoprolol and bisoprolol in hypertension . Methods 200 patients with hypertension were randomly divided into bisoprolol group and metoprolol group .Compared the clinical effect and the level of SBP and SDP before and after treatment of 2 groups.Results The clinical effect of 2 groups was no statistically significant(P >0.05).The level of SBP and SDP of 2 groups before treatment was no statistically significant (P >0.05).The level of SBP and SDP of 2 goups after treatment was lower than that before treatment ,and the level of SBP and SDP of bisoprolol group was lower than that of metoprolol group ,the difference was statistically significant (P <0.05). Conclusion Bisoprolol group has a good effect in keep 24h blood,worthy of clinical application.
