世界最新医学信息文摘(连续型电子期刊)
世界最新醫學信息文摘(連續型電子期刊)
세계최신의학신식문적(련속형전자기간)
World Latest Medicine Information
2014年
23期
43-44
,共2页
窦口鼻道复合体%结缔组织生长因子%免疫组织化学%光密度
竇口鼻道複閤體%結締組織生長因子%免疫組織化學%光密度
두구비도복합체%결체조직생장인자%면역조직화학%광밀도
Ostiomeatalex%connective tissue growth factor%Immunohistochemistry%optical density
目的:旨在通过研究鼻内窥镜手术中窦口鼻道复合体(ostiomeatalex oMc)解剖结构变异的程度和局部结缔组织生长因子(connective tissue growth factor,ctGf)表达的强度之间的关系。从而了解 ctGf 在 oMc 结构异常和局部炎性病变之间所起作用。方法将手术患者根据 oMc 变异程度分为两组,oMc 变异患者为 a 组,无明显变异者为B 组。通过免疫组织化学法对两组样本进行处理,通过对两组黏膜上皮细胞和粘膜下腺体细胞阳性细胞计数(%)及对 imageJ 光密度测定,sPss 统计软件进行统计学分析。结果 a 组患者黏膜细胞及黏膜下腺体细胞阳性率及光密度值均高于 B 组患者。结论 oMc 结构异常和局部 ctGf 表达有关,从而表明局部 ctGf 增多可能是 oMc 引起局部炎性增生性病变原因之一。
目的:旨在通過研究鼻內窺鏡手術中竇口鼻道複閤體(ostiomeatalex oMc)解剖結構變異的程度和跼部結締組織生長因子(connective tissue growth factor,ctGf)錶達的彊度之間的關繫。從而瞭解 ctGf 在 oMc 結構異常和跼部炎性病變之間所起作用。方法將手術患者根據 oMc 變異程度分為兩組,oMc 變異患者為 a 組,無明顯變異者為B 組。通過免疫組織化學法對兩組樣本進行處理,通過對兩組黏膜上皮細胞和粘膜下腺體細胞暘性細胞計數(%)及對 imageJ 光密度測定,sPss 統計軟件進行統計學分析。結果 a 組患者黏膜細胞及黏膜下腺體細胞暘性率及光密度值均高于 B 組患者。結論 oMc 結構異常和跼部 ctGf 錶達有關,從而錶明跼部 ctGf 增多可能是 oMc 引起跼部炎性增生性病變原因之一。
목적:지재통과연구비내규경수술중두구비도복합체(ostiomeatalex oMc)해부결구변이적정도화국부결체조직생장인자(connective tissue growth factor,ctGf)표체적강도지간적관계。종이료해 ctGf 재 oMc 결구이상화국부염성병변지간소기작용。방법장수술환자근거 oMc 변이정도분위량조,oMc 변이환자위 a 조,무명현변이자위B 조。통과면역조직화학법대량조양본진행처리,통과대량조점막상피세포화점막하선체세포양성세포계수(%)급대 imageJ 광밀도측정,sPss 통계연건진행통계학분석。결과 a 조환자점막세포급점막하선체세포양성솔급광밀도치균고우 B 조환자。결론 oMc 결구이상화국부 ctGf 표체유관,종이표명국부 ctGf 증다가능시 oMc 인기국부염성증생성병변원인지일。
objective our test is discover the correlation between the ctGf’s express and the abnormal of oMc in the sinus endoscope surgery. through this test ,we can learn ctGf’s role in the correlation between the oMc’ abnormal and inflammation in part. Methods Patients were divided to 2 groups according to abnormal of oMc. Group a include those patients whose oMc is abnormal.Group B include those patients whose oMc is normal. through immunohistochemistry ,and percentage of positive cells were calculated under the high power lens .analyse the optical density through the imageJ analyse system .the data was analyse by sPss statistics software. results the ctGf masculine rate and optical density of group a are higher than group B. conclusion ctGf’s over expression is correlation with oMc’s abnormal,this perhaps can discover ctGf’s over expression is one of the reason that oMc’s abnormal can cause nasosinusitis.