CAJ | 학술논문

目的：探讨吸烟和戒烟对门诊初治培阳肺结核患者治疗结果的影响。方法102例门诊吸烟初治培阳肺结核患者分为吸烟组和戒烟组,吸烟组根据吸烟指数再分为两个亚组(第1组,200年支≤吸烟指数<800年支,28例；第2组,吸烟指数≥800年支,26例),对两组患者的2个月末痰菌培养的痰菌阴转率对比分析。结果吸烟组2个月末痰菌培养阴转率(87.0%),明显低于戒烟组(95.8%),两组相比差异具有统计学意义(P<0.05)。吸烟指数≥800年支组痰培养阴转率(80.7%)明显低于吸烟指数200年支≤吸烟指数<800年支组(92.8%),两组相比差异具有统计学意义(P<0.05)。结论吸烟是使门诊初治培阳肺结核患者2个月痰菌培阳性率增高的重要因素,并影响化疗效果。提倡戒烟是减少肺结核传染源、保护易感人群的简单而有效的方法。
목적：탐토흡연화계연대문진초치배양폐결핵환자치료결과적영향。방법102례문진흡연초치배양폐결핵환자분위흡연조화계연조,흡연조근거흡연지수재분위량개아조(제1조,200년지≤흡연지수<800년지,28례；제2조,흡연지수≥800년지,26례),대량조환자적2개월말담균배양적담균음전솔대비분석。결과흡연조2개월말담균배양음전솔(87.0%),명현저우계연조(95.8%),량조상비차이구유통계학의의(P<0.05)。흡연지수≥800년지조담배양음전솔(80.7%)명현저우흡연지수200년지≤흡연지수<800년지조(92.8%),량조상비차이구유통계학의의(P<0.05)。결론흡연시사문진초치배양폐결핵환자2개월담균배양성솔증고적중요인소,병영향화료효과。제창계연시감소폐결핵전염원、보호역감인군적간단이유효적방법。
Objective To investigate the influence of smoking and smoking cessation on the treatment outcome on outpatient culture positive pulmonary tuberculosis.Methods A total of 102 patients with outpatient culture positive pulmonary tuberculosis were divided into smoking group and smoking cessation group. The smoking group was further divided into two subgroups (group 1 contains 28 cases, 200 cigarettes per year≤smoking index<800 cigarettes per year; group 2 contains 26 cases, smoking index≥800 cigarettes per year). An analysis was made on the comparison between the sputum negative conversion rates of the two groups after 2 months.Results The sputum negative conversion rates of the smoking group after 2 months (87.0%) was lower than that of the smoking cessation group (95.8%), and the difference had statistical significance (P<0.05). Group 2 with smoking index≥800 cigarettes per year had lower sputum negative conversion rates (80.7%) than that of group 1 with smoking index <800 cigarettes per year (92.8%). The difference had statistical significance (P<0.05).Conclusion Smoking is the main factor of the higher sputum negative conversion rates for the patients with outpatient culture positive pulmonary tuberculosis and the influence on chemotherapy effect. Advocating smoking cessation is a simple and effective way to reduce pulmonary tuberculosis infection source, and to protect susceptible population.