CAJ | 학술논문

目的：探讨单腔深静脉管置入引流联合聚桂醇硬化治疗巨大肝肾囊肿的不良反应及疗效。方法选取2006年1月-2009年12月江苏大学附属医院收治的巨大肝肾囊肿患者31例为对照组，2010年1月-2013年1月收治的巨大肝肾囊肿患者32例为研究组，均置入单腔深静脉管，充分引流后对照组注入无水乙醇、研究组注入聚桂醇进行硬化治疗，观察并记录治疗过程中患者不良反应及术后6个月的治疗效果。结果对照组9例（29.0%）患者出现轻中度腹痛、面红、心悸、头晕、恶心等表现；研究组2例（6.2%）患者出现穿刺部位轻度胀痛不适，无腹痛、无醉酒样反应。两组患者不良反应发生率比较，差异有统计学意义（χ2=5.671，P=0.017）。术后6个月复查B超或CT，研究组25例治愈，7例有效；对照组24例治愈，7例有效。两组治疗效果比较，差异无统计学意义（ u=-0.067，P=0.947）。结论单腔深静脉管置入引流联合聚桂醇硬化治疗巨大肝肾囊肿简单、安全、有效，聚桂醇疗效与无水乙醇相当，但不良反应更少，患者对其耐受性更好。
목적：탐토단강심정맥관치입인류연합취계순경화치료거대간신낭종적불량반응급료효。방법선취2006년1월-2009년12월강소대학부속의원수치적거대간신낭종환자31례위대조조，2010년1월-2013년1월수치적거대간신낭종환자32례위연구조，균치입단강심정맥관，충분인류후대조조주입무수을순、연구조주입취계순진행경화치료，관찰병기록치료과정중환자불량반응급술후6개월적치료효과。결과대조조9례（29.0%）환자출현경중도복통、면홍、심계、두훈、악심등표현；연구조2례（6.2%）환자출현천자부위경도창통불괄，무복통、무취주양반응。량조환자불량반응발생솔비교，차이유통계학의의（χ2=5.671，P=0.017）。술후6개월복사B초혹CT，연구조25례치유，7례유효；대조조24례치유，7례유효。량조치료효과비교，차이무통계학의의（ u=-0.067，P=0.947）。결론단강심정맥관치입인류연합취계순경화치료거대간신낭종간단、안전、유효，취계순료효여무수을순상당，단불량반응경소，환자대기내수성경호。
Objective To study the therapeutic effects and adverse reactions of drainage by deep vein single lumen tube and lauromacrogol sclerotherapy in the treatment of large hepatic or renal cysts. Methods 31 patients with large hepatic or renal cysts admitted to the Affiliated Hospital of Jiangsu University from January 2006 to December 2009 were selected as control group,while 32 patients with large hepatic or renal cysts admitted from January 2010 to January 2013 were selected as study group. The two groups were both placed with deep vein single lumen tube. After fully drainage,the control group was injected with anhydrous alcohol while the study group was injected with lauromacrogol to have sclerotherapy. The adverse reactions and the ther-apeutic effect after six months were both recorded. Results 9 cases ( 29. 0%)in the control group showed moderate stomach-ache,flushed face,palpitation,dizziness and nausea. 2 cases(6. 2%)in the study group showed mild distending pain in the injection site,but showed no stomachache and drunk-like response. The adverse reaction rate between the two groups showed statistically significant differences(χ2 =5. 671,P=0. 017). Type-B ultrasound or CT six months after treatment showed that 25 cases were cured and 7 cases were improved in the study group,while 24 cases were cured and 7 cases were improved in the control group. The therapeutic effect between the two groups showed no statistically significant difference( u = -0. 067,P =0. 947 ) . Conclusion The drainage by deep vein single lumen tube and lauromacrogol sclerotherapy in the treatment of large he-patic or renal cysts is simple,safe and effective. The effect of lauromacrogol and anhydrous alcohol is pretty much the same,but has fewer adverse reactions and better tolerance.