中国医药指南
中國醫藥指南
중국의약지남
CHINA MEDICINE GUIDE
2013年
26期
30-31
,共2页
消化性溃疡%心理干预%抑郁%临床疗效
消化性潰瘍%心理榦預%抑鬱%臨床療效
소화성궤양%심리간예%억욱%림상료효
Peptic ulcer%Mental intervention%Depression%Clinical curative effect
目的：探讨心理干预结合小剂量抗抑郁药物治疗消化性溃疡的临床疗效。方法以我院2006年6月至2012年10月收治的148例消化性溃疡患者作为研究对象。随机分为对照组（74例）和治疗组（74例）。对照组采用单纯常规药物治疗，治疗组在常规药物治疗基础上结合心理干预和小剂量抗抑郁药物治疗。分别观察两组患者在疗效上的差异情况。结果所有患者在治疗2个月后进行复查。治疗组治愈57例，有效14例，无效3例，总有效率95.9%；对照组治愈47例，有效17例，无效10例，总有效率86.5%；两组在治愈率和总体有效率上比较差异有统计学意义（P<0.05）。治疗后6个月后随访，治疗组复发率（7.0%）低于对照组（14.9%）（P<0.05）。结论消化性溃疡患者常存在焦虑抑郁心理问题，在积极进行常规内科治疗的同时，结合心理干预和小剂量抗抑郁药物治疗，能更好地提高疗效，促进溃疡的愈合。
目的：探討心理榦預結閤小劑量抗抑鬱藥物治療消化性潰瘍的臨床療效。方法以我院2006年6月至2012年10月收治的148例消化性潰瘍患者作為研究對象。隨機分為對照組（74例）和治療組（74例）。對照組採用單純常規藥物治療，治療組在常規藥物治療基礎上結閤心理榦預和小劑量抗抑鬱藥物治療。分彆觀察兩組患者在療效上的差異情況。結果所有患者在治療2箇月後進行複查。治療組治愈57例，有效14例，無效3例，總有效率95.9%；對照組治愈47例，有效17例，無效10例，總有效率86.5%；兩組在治愈率和總體有效率上比較差異有統計學意義（P<0.05）。治療後6箇月後隨訪，治療組複髮率（7.0%）低于對照組（14.9%）（P<0.05）。結論消化性潰瘍患者常存在焦慮抑鬱心理問題，在積極進行常規內科治療的同時，結閤心理榦預和小劑量抗抑鬱藥物治療，能更好地提高療效，促進潰瘍的愈閤。
목적：탐토심리간예결합소제량항억욱약물치료소화성궤양적림상료효。방법이아원2006년6월지2012년10월수치적148례소화성궤양환자작위연구대상。수궤분위대조조（74례）화치료조（74례）。대조조채용단순상규약물치료，치료조재상규약물치료기출상결합심리간예화소제량항억욱약물치료。분별관찰량조환자재료효상적차이정황。결과소유환자재치료2개월후진행복사。치료조치유57례，유효14례，무효3례，총유효솔95.9%；대조조치유47례，유효17례，무효10례，총유효솔86.5%；량조재치유솔화총체유효솔상비교차이유통계학의의（P<0.05）。치료후6개월후수방，치료조복발솔（7.0%）저우대조조（14.9%）（P<0.05）。결론소화성궤양환자상존재초필억욱심리문제，재적겁진행상규내과치료적동시，결합심리간예화소제량항억욱약물치료，능경호지제고료효，촉진궤양적유합。
Objective?To investigates the clinical effects of combination of psychological and small doses of antidepressanton patients with peptic ulcer. Methods 148 patients with peptic ulcer, who treated in our hospital from June 2006 to October 2012, were divided into two groups randomly. The control group was treated only by conventional medicaments;the treatmentgroup was treated by conventional medicaments in combination with psychological and small doses of antidepressant. Results After 2 months of treatment, there were 57 patients were cured and 14 cases improved in treatmentgroup, and the total effective rate was 95.9%. In control group, there were 47 patients were cured and 17 cases improved, and the total effective rate was 86.5%. The statistically significantdifference was detected between the two groups in terms of cure rate and total effective rate (P<0.05). The follow-up after 6 months of treatmentshowed thatthe recurrence rate of treatmentgroup was lower than thatof in control group (P<0.05). Conclusion Many patients with peptic ulcer usually have psychological problems such as anxiety and depression. Treatmentof conventional medicaments in combination with psychological and small doses of antidepressantcould improve the clinical effectand the healing of peptic ulcer.
