CAJ | 학술논문

目的探讨经尿道膀胱肿瘤电切术联合沙培林膀胱黏膜下注射治疗浅表性膀胱肿瘤的疗效.方法将85例膀胱肿瘤患者分为两组(A组和B组),A组42例,B组43例,两组均行经尿道膀胱肿瘤电切术,A组另用5KE沙培林溶于50ml0.9％ Nacl溶液行膀胱黏膜下注射.两组术后均行沙培林膀胱灌注,膀胱内灌注保留2h,每周1次,连续8周,以后每月灌一次,连续10个月.根据随访结果对两种方法的疗效进行评价.结果 A组平均随访24个月,B组平均随访26个月.A组随访期内复发4例(9.52％),B组随访期内复发16例(37.2％),A组复发率与B组比较,差异有统计学意义(P＜0.05).结论经尿道电切联合沙培林黏膜下注射可减少膀胱肿瘤复发,操作简单,安全有效.
목적 탐토경뇨도방광종류전절술연합사배림방광점막하주사치료천표성방광종류적료효.방법 장85례방광종류환자분위량조(A조화B조),A조42례,B조43례,량조균행경뇨도방광종류전절술,A조령용5KE사배림용우50ml0.9％ Nacl용액행방광점막하주사.량조술후균행사배림방광관주,방광내관주보류2h,매주1차,련속8주,이후매월관일차,련속10개월.근거수방결과대량충방법적료효진행평개.결과 A조평균수방24개월,B조평균수방26개월.A조수방기내복발4례(9.52％),B조수방기내복발16례(37.2％),A조복발솔여B조비교,차이유통계학의의(P＜0.05).결론 경뇨도전절연합사배림점막하주사가감소방광종류복발,조작간단,안전유효.
Objectives To investigate the efficacy by studying electrovaporization of bladder cancer and transurethral injeetan of OK-432.Methods 42 case of bladder cancer received the OK-432 solution injected to the pedicle of bladder tumor after operation,and 43 cases only received operation,do not give the OK-432 solution injected to the pedicle of bladder tumor.Both groups received OK-432 routine treatment,the effects Were evaluated according to recurrence ratio.Results Injection group had a mean follow-up of 24 months,control group had mean follow-up of 26 months,The recurrence rate of injection group was 9.52％ (4/42),and that of the control group was 37.2 (16/43).There is a very significant difference between the two groups(P ＜0.05).Conclusions Operation combined with OK-432 injection are simple and safe for the treatment of superficial bladder cancer,can increase the efficacy,and reduce recurren rate.