世界最新医学信息文摘(电子版)
世界最新醫學信息文摘(電子版)
세계최신의학신식문적(전자판)
World Latest Medicine Information
2013年
27期
22-22,19
,共2页
甲亢%碘131%精神障碍
甲亢%碘131%精神障礙
갑항%전131%정신장애
hyperthyroidism%iodine 131%mental disturbance
目的:为有效治疗甲亢合并精神障碍患者,避免两种疾病同时发作和长期服药对身体造成严重损害,尽早治愈甲亢后,使患者精神障碍明显缓解或治愈有效缩短病程。利用碘131对甲亢合并精神障碍者15例,在治疗精神障碍的同时,给于口服碘131治疗。方法对于已经确诊的甲亢合并精神病患者,在常规抗精神病药物对症治疗的同时进行血清 ft3、ft4、tsH、traB。肝功能、肾功能、K+、na+、cl-、血糖、血常规及心电图,甲状腺彩超或甲状腺 ect显像,以及碘131吸收收率试验等,以确定碘131口服剂量,同时住院观察一周至10天左右。结果15例患者除2例服用二次碘131外,其余13例均一次服用碘131治愈,治疗过程为半年至1年,其中甲低1例。对精神障碍进行随访二年以上,11例狂躁症患者未再明显发作,以脱离药物治疗。4例抑郁症患者除1例间断发作外,另外3例也未再发作,疗效满意。结论在甲亢合并精神障碍疾病治疗上,为缩短病程减少同时服药和两种疾病同时发作,对身体造成的损害,可以首选碘131治疗甲亢的同时,再对症治疗精神障碍。甲亢疾病治愈后精神障碍可以自行缓解或减轻。
目的:為有效治療甲亢閤併精神障礙患者,避免兩種疾病同時髮作和長期服藥對身體造成嚴重損害,儘早治愈甲亢後,使患者精神障礙明顯緩解或治愈有效縮短病程。利用碘131對甲亢閤併精神障礙者15例,在治療精神障礙的同時,給于口服碘131治療。方法對于已經確診的甲亢閤併精神病患者,在常規抗精神病藥物對癥治療的同時進行血清 ft3、ft4、tsH、traB。肝功能、腎功能、K+、na+、cl-、血糖、血常規及心電圖,甲狀腺綵超或甲狀腺 ect顯像,以及碘131吸收收率試驗等,以確定碘131口服劑量,同時住院觀察一週至10天左右。結果15例患者除2例服用二次碘131外,其餘13例均一次服用碘131治愈,治療過程為半年至1年,其中甲低1例。對精神障礙進行隨訪二年以上,11例狂躁癥患者未再明顯髮作,以脫離藥物治療。4例抑鬱癥患者除1例間斷髮作外,另外3例也未再髮作,療效滿意。結論在甲亢閤併精神障礙疾病治療上,為縮短病程減少同時服藥和兩種疾病同時髮作,對身體造成的損害,可以首選碘131治療甲亢的同時,再對癥治療精神障礙。甲亢疾病治愈後精神障礙可以自行緩解或減輕。
목적:위유효치료갑항합병정신장애환자,피면량충질병동시발작화장기복약대신체조성엄중손해,진조치유갑항후,사환자정신장애명현완해혹치유유효축단병정。이용전131대갑항합병정신장애자15례,재치료정신장애적동시,급우구복전131치료。방법대우이경학진적갑항합병정신병환자,재상규항정신병약물대증치료적동시진행혈청 ft3、ft4、tsH、traB。간공능、신공능、K+、na+、cl-、혈당、혈상규급심전도,갑상선채초혹갑상선 ect현상,이급전131흡수수솔시험등,이학정전131구복제량,동시주원관찰일주지10천좌우。결과15례환자제2례복용이차전131외,기여13례균일차복용전131치유,치료과정위반년지1년,기중갑저1례。대정신장애진행수방이년이상,11례광조증환자미재명현발작,이탈리약물치료。4례억욱증환자제1례간단발작외,령외3례야미재발작,료효만의。결론재갑항합병정신장애질병치료상,위축단병정감소동시복약화량충질병동시발작,대신체조성적손해,가이수선전131치료갑항적동시,재대증치료정신장애。갑항질병치유후정신장애가이자행완해혹감경。
Objective in order to avoid the harm that hyperthyroidism with mental disturbance long-term medication and coincide, cure hyperthyroidism, shorten the duration of symptoms are impotant to alleviate or cure the symptom of the people with mental disorders. Method 15 cases of patients with hyperthyroidism and mental disturbance were for oral iodine 131 treatment at the same time in the treatment of mental disorders. through the detection function of liver,renal, serum potassium,serum natrium,serum chlorine, blood glucose, blood routine,ecG, color doppler ultrasound, ect and iodine 131 absorption yield trials to determine the dosesof iodine 131.measure the ft3、ft4、tsH、traB at the same time.observe 7-10 days at the in-patient department.result: except 2 patients taking secondary iodine 131, the rest of the 13 patients were cured only one taking iodine 131 for once. the time of therapy is about six months to one year, followed up for 2 years, 11 patients with mania were out of drug treatment and no attack again,exccept 1 patient intermittent episodes of depression,the rest of 4patients were cured. Conclusion For the patients of hyperthyroidism with mental disturbance, Iodine 131 is the first choice, not merely shorten the duration, avoid the harm but also give opportunity for the treatment of mental diseases, improve the quality of life of patients.