齐齐哈尔医学院学报
齊齊哈爾醫學院學報
제제합이의학원학보
JOURNAL OF QIQIHAR MEDICAL COLLEGE
2014年
5期
672-673
,共2页
小儿%传染性单核细胞增多症%临床特点%误诊分析
小兒%傳染性單覈細胞增多癥%臨床特點%誤診分析
소인%전염성단핵세포증다증%림상특점%오진분석
Children%Infectious mononucleosis%Clinical characteristics%Misdiagnosis analysis
目的:探讨小儿传染性单核细胞增多症( IM )的临床特点,以早期诊断,减少误诊。方法对入院前误诊、入院后确诊为IM的55例患儿进行误诊情况分析。结果 IM临床表现多样,其主要表现为:发热55例(100%),咽峡炎40例(72.73%),淋巴结肿大45例(81.82%),肝脏肿大30例(54.55%),脾脏肿大23例(41.82%),皮疹9例(16.36%),鼻塞15例(27.27%),眼睑浮肿10例(18.18%)。实验室检查:外周血常规白细胞数>10×109/L者70.91%(39例),异形淋巴细胞检查>10%者100%(55例),EBV-VCA-IgM检测阳性100%(55例),可伴血小板减少、肝功能受损、肺炎等。早期无特异性临床表现,早期确诊难,外周血异常淋巴细胞>10%和 EBV-VCA-IgM 阳性可协助诊断。结论 IM临床表现复杂多样,可伴多器官多系统损害。详细的体格检查和及时的实验室检查可提高诊断率。
目的:探討小兒傳染性單覈細胞增多癥( IM )的臨床特點,以早期診斷,減少誤診。方法對入院前誤診、入院後確診為IM的55例患兒進行誤診情況分析。結果 IM臨床錶現多樣,其主要錶現為:髮熱55例(100%),嚥峽炎40例(72.73%),淋巴結腫大45例(81.82%),肝髒腫大30例(54.55%),脾髒腫大23例(41.82%),皮疹9例(16.36%),鼻塞15例(27.27%),眼瞼浮腫10例(18.18%)。實驗室檢查:外週血常規白細胞數>10×109/L者70.91%(39例),異形淋巴細胞檢查>10%者100%(55例),EBV-VCA-IgM檢測暘性100%(55例),可伴血小闆減少、肝功能受損、肺炎等。早期無特異性臨床錶現,早期確診難,外週血異常淋巴細胞>10%和 EBV-VCA-IgM 暘性可協助診斷。結論 IM臨床錶現複雜多樣,可伴多器官多繫統損害。詳細的體格檢查和及時的實驗室檢查可提高診斷率。
목적:탐토소인전염성단핵세포증다증( IM )적림상특점,이조기진단,감소오진。방법대입원전오진、입원후학진위IM적55례환인진행오진정황분석。결과 IM림상표현다양,기주요표현위:발열55례(100%),인협염40례(72.73%),림파결종대45례(81.82%),간장종대30례(54.55%),비장종대23례(41.82%),피진9례(16.36%),비새15례(27.27%),안검부종10례(18.18%)。실험실검사:외주혈상규백세포수>10×109/L자70.91%(39례),이형림파세포검사>10%자100%(55례),EBV-VCA-IgM검측양성100%(55례),가반혈소판감소、간공능수손、폐염등。조기무특이성림상표현,조기학진난,외주혈이상림파세포>10%화 EBV-VCA-IgM 양성가협조진단。결론 IM림상표현복잡다양,가반다기관다계통손해。상세적체격검사화급시적실험실검사가제고진단솔。
Objective To investigate the clinical characteristics of children infectious mononucleosis (IM), in order to diagnose at early stage and reduce misdiagnosis .Methods Misdiagnosis analysis was conducted on 55 cases of children who were misdiagnosed before admissionand diagnosed as infectious mononucleosisafter admission .Results The clinical manifestations of children infectiousmononucleosiswere diversified, consisting fever ( 55, 100%), isthmitis ( 40, 72.73%), lymphadenectasis ( 45, 81.82%), hepatomegaly(30,54.55%), splenomegaly(23,41.82%),skin rash(9,16.36%),rhinobyon (15,27.27%), palpebral edema (10,18.18%).Laboratory examinations indicated that peripheral blood white blood c ells (WBC) were more than 10 ×109/L ( n =39 ), all the patients were found heteromorphous lymphocyte percentagewas higher than 10%and EBV -IgM positive .some patients were complicated by thrombocytopenia , pneumonia and impairment of liver function , etc.Infectious mononucleosis at early stage present no specific clinical manifestation ,so it was difficult to make an early diagnosis .Abnormallymphocytes in peripheral blood more than 10% and EBV -IgM positive could assist for the diagnosis .Conclusions The clinical manifestation of infectious mononucleosis is complicated and diversified .And might be companied by multiple organ dysfunction . Detailed physical examination and laboratory examination can improve the diagnosis rate .