CAJ | 학술논문

目的：探讨全自动持续正压呼吸机（ cpap）对脑梗死合并阻塞性睡眠呼吸暂停低通气综合征（ OSAHS）患者纤溶系统及脑梗死再发影响。方法将我院收治的100例脑梗死合并OSAHS患者随机分为两组。试验组50例进行cpap干预。对照组50例未给予cpap干预。比较两组脑梗死再发的差异。同时评价两组纤溶系统情况。结果试验组脑梗死再发率6．0％低于对照组22．0％，有统计学差异（ P＜0．05）；治疗后试验组t-PA显著升高，有统计学差异（P＜0．05）。同时其也高于同期对照组，有统计学差异（P＜0．05）；治疗后试验组PAI-1显著降低，有统计学差异（P＜0．05）。同时其也低于同期对照组，有统计学差异（P＜0．05）。结论 cpap干预对脑梗死合并OSAHS患者疗效显著。其能够有效改善患者纤溶系统。进而减轻患者高凝状态。同时也能够降低患者脑梗死再发率。从而有效改善患者生活质量及生存质量。
목적：탐토전자동지속정압호흡궤（ cpap）대뇌경사합병조새성수면호흡잠정저통기종합정（ OSAHS）환자섬용계통급뇌경사재발영향。방법장아원수치적100례뇌경사합병OSAHS환자수궤분위량조。시험조50례진행cpap간예。대조조50례미급여cpap간예。비교량조뇌경사재발적차이。동시평개량조섬용계통정황。결과시험조뇌경사재발솔6．0％저우대조조22．0％，유통계학차이（ P＜0．05）；치료후시험조t-PA현저승고，유통계학차이（P＜0．05）。동시기야고우동기대조조，유통계학차이（P＜0．05）；치료후시험조PAI-1현저강저，유통계학차이（P＜0．05）。동시기야저우동기대조조，유통계학차이（P＜0．05）。결론 cpap간예대뇌경사합병OSAHS환자료효현저。기능구유효개선환자섬용계통。진이감경환자고응상태。동시야능구강저환자뇌경사재발솔。종이유효개선환자생활질량급생존질량。
Objective To explore Effect of CPAP intervention on fibrinolytic system of patients with recurrent cerebral infarction complicated with OSAH .Methods Divided randomly 100 patients of cerebral infarction with OSAHS in our hospital into two groups .50 cases of test group CPAP intervention .50 cases in control group were not given CPAP intervention , differences between the two groups of recurrent cerebral infarction.At the same time evaluation of two groups of fibrinolytic system .Results The experimental group of cerebral infarction recurrence rate was 6% lower than that of the control group was 22%, there was significant difference (P<0.05); experimental group after treatment , t-PA were significantly increased, with significant difference (P<0.05).At the same time it was also higher than those in the control group , there was statistically significant difference (P<0.05); experimental group after treatment, PAI-1 decreased; there was significant difference (P<0.05).At the same time it also lower than the same period in the control group , there was statistically significant difference ( P <0.05 ).Conclusions CPAP intervention on cerebral infarction with OSAHS effect.It can effectively improve the fibrinolytic system , and relieve the hypercoagulable patients'state,meanwhile , reduce the rate of recurrence in patients with cerebral infarction , and improve the quality of life of patients.