中国医学装备
中國醫學裝備
중국의학장비
CHINA MEDICAL EQUIPMENT
2014年
4期
90-92
,共3页
LED紫外线%药物%白癜风%治疗效果
LED紫外線%藥物%白癜風%治療效果
LED자외선%약물%백전풍%치료효과
Ultraviolet LED%Drug%Vitiligo%Therapeutic effect
目的：观察比较308nm LED窄谱中波紫外线联用他克莫司与365nm LED窄谱长波紫外线联用8-甲氧补骨脂素照射治疗白癜风的临床疗效。方法：选取64例白癜风患者采用随机数字表法分为对照组及观察组，每组32例，对照组采用308nm LED窄谱中波紫外线联用他克莫司照射治疗，观察组采用365nm LED窄谱长波紫外线联用8-甲氧补骨脂素照射治疗，对比两组患者治疗后出现第一个色素岛的照射次数以及治疗10次、20次后的临床疗效。结果：观察组与对照组出现第一个色素岛的平均照射次数分别为5.59和6.24次，其差异无统计学意义(t=1.772，P＞0.05)。对照组治疗20次后有效率为37.50％，观察组治疗20次后有效率为40．63％，两种治疗方法的治疗效果差异无统计学意义(x2=0.000，P＞0.05)。结论：308nm LED窄谱中波紫外线联用他克莫司与365nm LED窄谱长波紫外线联用8-甲氧补骨脂素照射治疗白癜风均具有显著的临床治疗效果，如何提高治疗效果尚需进一步深入研究。
目的：觀察比較308nm LED窄譜中波紫外線聯用他剋莫司與365nm LED窄譜長波紫外線聯用8-甲氧補骨脂素照射治療白癜風的臨床療效。方法：選取64例白癜風患者採用隨機數字錶法分為對照組及觀察組，每組32例，對照組採用308nm LED窄譜中波紫外線聯用他剋莫司照射治療，觀察組採用365nm LED窄譜長波紫外線聯用8-甲氧補骨脂素照射治療，對比兩組患者治療後齣現第一箇色素島的照射次數以及治療10次、20次後的臨床療效。結果：觀察組與對照組齣現第一箇色素島的平均照射次數分彆為5.59和6.24次，其差異無統計學意義(t=1.772，P＞0.05)。對照組治療20次後有效率為37.50％，觀察組治療20次後有效率為40．63％，兩種治療方法的治療效果差異無統計學意義(x2=0.000，P＞0.05)。結論：308nm LED窄譜中波紫外線聯用他剋莫司與365nm LED窄譜長波紫外線聯用8-甲氧補骨脂素照射治療白癜風均具有顯著的臨床治療效果，如何提高治療效果尚需進一步深入研究。
목적：관찰비교308nm LED착보중파자외선련용타극막사여365nm LED착보장파자외선련용8-갑양보골지소조사치료백전풍적림상료효。방법：선취64례백전풍환자채용수궤수자표법분위대조조급관찰조，매조32례，대조조채용308nm LED착보중파자외선련용타극막사조사치료，관찰조채용365nm LED착보장파자외선련용8-갑양보골지소조사치료，대비량조환자치료후출현제일개색소도적조사차수이급치료10차、20차후적림상료효。결과：관찰조여대조조출현제일개색소도적평균조사차수분별위5.59화6.24차，기차이무통계학의의(t=1.772，P＞0.05)。대조조치료20차후유효솔위37.50％，관찰조치료20차후유효솔위40．63％，량충치료방법적치료효과차이무통계학의의(x2=0.000，P＞0.05)。결론：308nm LED착보중파자외선련용타극막사여365nm LED착보장파자외선련용8-갑양보골지소조사치료백전풍균구유현저적림상치료효과，여하제고치료효과상수진일보심입연구。
Objective:To observe the clinical curative effect of narrow-band UVB-LED (308nm) combined with tacrolimus, narrow-band UVA-LED (365nm) combined with 8-Methoxypsoralen irradiation in the treatment of vitiligo.Methods: Sixty-four cases of vitiligo patients were chosen and randomly divided into control group and observation group, each group with 32 cases. The control group received 308nm narrow-band UVB-LED irradiation combined with tacrolimus,the observation group received 365nm narrow-band UVA-LED irradiation combined with 8-Methoxypsoralen, the time of appreance of the first pigment island in patients were compared between the two groups,the clinical curative effect of both groups were observed when treated with 10 times and 20 times.Results: The average irradiation times when first pigment island appreance in the observation group and the control group were 5.59 and 6.24 respectively, the difference was not statistically significant (t=1.772,P>0.05). The efficiency rate of the control group was 37.50% after 20 times treatment, and in the observation group was 40.63%, the difference was not statistically significant (x2=0.000,P>0.05).Conclusion: 308nm narrow band UVB-LED combined with tacrolimus and 365nm narrow-band UVA- LED combined with 8- Methoxypsoralen irradiation in the treatment of vitiligo have significant treatment effects, how to improve the treatment effect still need further study.
