临床合理用药杂志
臨床閤理用藥雜誌
림상합리용약잡지
CHINESE JOURNAL OF CLINICAL RATIONAL DRUG USE
2014年
20期
29-30
,共2页
肺炎%盐酸氨溴索%给药方式
肺炎%鹽痠氨溴索%給藥方式
폐염%염산안추색%급약방식
Pneumonia%Ambroxol hydrochloride%Administration mode
目的：比较盐酸氨溴索不同给药方式辅助治疗小儿肺炎的临床效果。方法收集2012年8月-2013年12月医院治疗的小儿肺炎患儿180例，按照随机数字表法分为4组：A 组、B 组、C 组、D 组各45例。所有患儿均给予基础综合治疗，在此基础上，A 组口服盐酸氨溴索治疗，B 组采用盐酸氨溴索静脉给药治疗，C 组采用盐酸氨溴索雾化吸入给药治疗，D 组不给于盐酸氨溴索治疗。结果 A 组、B 组、C 组临床症状、体征消失时间及住院时间均明显短于 D 组，差异有统计学意义（P ﹤0.05）；C 组咳嗽消失时间、肺部啰音消失时间、胸部 X 线片恢复正常时间、住院均明显短于 A 组、B 组，差异有统计学意义（P ﹤0.05）。A 组、B 组、C 组显效率及总有效率均明显高于 D 组，差异有统计学意义（P ﹤0.05）；C 组显效率明显高于 A 组、B 组，差异有统计学意义（P ﹤0.05）。结论采用盐酸氨溴索雾化吸入治疗小儿肺炎效果较好，安全性高，可以在临床推广应用。
目的：比較鹽痠氨溴索不同給藥方式輔助治療小兒肺炎的臨床效果。方法收集2012年8月-2013年12月醫院治療的小兒肺炎患兒180例，按照隨機數字錶法分為4組：A 組、B 組、C 組、D 組各45例。所有患兒均給予基礎綜閤治療，在此基礎上，A 組口服鹽痠氨溴索治療，B 組採用鹽痠氨溴索靜脈給藥治療，C 組採用鹽痠氨溴索霧化吸入給藥治療，D 組不給于鹽痠氨溴索治療。結果 A 組、B 組、C 組臨床癥狀、體徵消失時間及住院時間均明顯短于 D 組，差異有統計學意義（P ﹤0.05）；C 組咳嗽消失時間、肺部啰音消失時間、胸部 X 線片恢複正常時間、住院均明顯短于 A 組、B 組，差異有統計學意義（P ﹤0.05）。A 組、B 組、C 組顯效率及總有效率均明顯高于 D 組，差異有統計學意義（P ﹤0.05）；C 組顯效率明顯高于 A 組、B 組，差異有統計學意義（P ﹤0.05）。結論採用鹽痠氨溴索霧化吸入治療小兒肺炎效果較好，安全性高，可以在臨床推廣應用。
목적：비교염산안추색불동급약방식보조치료소인폐염적림상효과。방법수집2012년8월-2013년12월의원치료적소인폐염환인180례，안조수궤수자표법분위4조：A 조、B 조、C 조、D 조각45례。소유환인균급여기출종합치료，재차기출상，A 조구복염산안추색치료，B 조채용염산안추색정맥급약치료，C 조채용염산안추색무화흡입급약치료，D 조불급우염산안추색치료。결과 A 조、B 조、C 조림상증상、체정소실시간급주원시간균명현단우 D 조，차이유통계학의의（P ﹤0.05）；C 조해수소실시간、폐부라음소실시간、흉부 X 선편회복정상시간、주원균명현단우 A 조、B 조，차이유통계학의의（P ﹤0.05）。A 조、B 조、C 조현효솔급총유효솔균명현고우 D 조，차이유통계학의의（P ﹤0.05）；C 조현효솔명현고우 A 조、B 조，차이유통계학의의（P ﹤0.05）。결론채용염산안추색무화흡입치료소인폐염효과교호，안전성고，가이재림상추엄응용。
Objective To compare the clinical results of different ambroxol hydrochloride administration mode in the adjuvant treatment of infantile pneumonia. Methods 180 cases of children with pneumonia were selected from August 2012 to December 2013 in our hospital and randomly divided into four groups:Group A,Group B,Group C,group D,each of 45 cases. All patients were given with basic therapy. The group A were oral ambroxol hydrochloride for treatment,group B received intra-venous therapy with ambroxol hydrochloride,group C received aerosol inhalation treatment with ambroxol inhalation,group D did not given ambroxol hydrochloride. Results The clinical symptoms and signs disappear time and hospital stay of group A, Group B and Group C were significantly shorter than in the group D,the difference was statistically significant(P ﹤ 0. 05);The cough disappeared time,pulmonary rales disappeared time,chest X-ray recovery time,hospital stay time of Group C were signif-icantly shorter than in group A,group B,the difference was statistically significant(P ﹤ 0. 05). The efficient rate and the total effective rate of group A,group B,group C were significantly higher than the group D,the difference was statistically significant (P ﹤ 0. 05),and the group C was significantly higher than group A,group B,the difference was statistically significant(P ﹤0. 05). Conclusion The aerosol inhalation treatment with ambroxol inhalation for infantile pneumonia has good curative effect,with higher security,which can be used in clinical practice.
