CAJ | 학술논문

目的：探讨小儿手足口病流行病学特征。方法以浙江省仙居县2013年度经临床和实验室确诊的589例手足口病患儿为研究对象，分析性别、年龄、发病月份、地区分布和临床表现等。结果仙居县该年度手足口病患病率为102.72/10万，其中12例为重症病例，无死亡病例；男女患儿比例为1.29∶1，男性明显多于女性，性别间患病率比较，差异有统计学意义（χ2＝14.274， P＜0.001）；患儿主要以0～3岁为主（94.74%）；发病时间集中在4-8月和11月，其中4月为高发期；发病地区以乡村和城郊地区为主，分别占45.50%和30.73%；患儿主要为幼托和散居儿童，分别占51.10%和40.92%；临床表现主要为发热和手、足、口及臀部不同程度的疱疹或丘疹。结论手足口病多发生在卫生知识相对缺乏地区，发病以年龄较小儿童为主，且具有一定季节性。
목적：탐토소인수족구병류행병학특정。방법이절강성선거현2013년도경림상화실험실학진적589례수족구병환인위연구대상，분석성별、년령、발병월빈、지구분포화림상표현등。결과선거현해년도수족구병환병솔위102.72/10만，기중12례위중증병례，무사망병례；남녀환인비례위1.29∶1，남성명현다우녀성，성별간환병솔비교，차이유통계학의의（χ2＝14.274， P＜0.001）；환인주요이0～3세위주（94.74%）；발병시간집중재4-8월화11월，기중4월위고발기；발병지구이향촌화성교지구위주，분별점45.50%화30.73%；환인주요위유탁화산거인동，분별점51.10%화40.92%；림상표현주요위발열화수、족、구급둔부불동정도적포진혹구진。결론수족구병다발생재위생지식상대결핍지구，발병이년령교소인동위주，차구유일정계절성。
Objective To investigate the epidemiological characteristics of hand-foot-mouth disease. Methods A total of 589 children from Xianju county,Zhejiang province with hand-foot-mouth disease in 2013 were recruited in the study and the diagnosis went through clinical and laboratory confirmation. Attributes that were analyzed included gender,age,month of occurrence, regional distribution and clinical presentation. Results The incidence rate of hand-foot-mouth disease in Xianju county for the year was 102.72/100 000,with 12 severe cases but no death. There were clearly more boys than girls,with a male to female ratio of 1.29∶1,which was statistically significant(χ2=14.274,P<0.001). The vast majority of patients were 0-3 years old,representing 94.74% of the patients. The occurrences were concentrated in the period from April to August and November,with April as the high-incidence season. High incidence areas were the countryside and suburbs,making up 45.50%and 30.73%,respectively,of all cases. Most patients were in preschools or scattered home care environments,accounting for 51.10% and 40.92% ,respectively. Clinical presentation was characterized by fever and various kinds of vesicles or papules at the hand,foot, mouth or buttocks. Conclusion Most of hand-foot-mouth disease cases occur in younger children in areas with inadequate knowledge of hygiene,with seasonal variation.