CAJ | 학술논문

目的：定量估计中国人群高血压的疾病负担。方法使用2010年全球疾病负担研究（GBD 2010）中国部分的方法和结果。利用人群平均收缩压、人群死亡、伤残损失寿命年（YLL）、早逝损失寿命年（YLD）和伤残调整寿命年（DALY）数据，以及校正了回归稀释系数的血压与相关疾病的联系强度数据，计算2010年中国人群归因于高血压的死亡、YLL、YLD和DALY。结果在所有心血管病死亡和DALY中，高血压的贡献为64.0%。2010年中国因高血压死亡共计204.3万例，其中男性115.4万例，女性88.9万例；心血管病死亡200.7万例，慢性肾病死亡3.5万例，由高血压导致的死亡占全部死亡的24.6%。中国人群因高血压造成的DALY高达3794万人年，其中男性为2332.6万人年，女性为1461.4万人年；YLD为236.5万人年，YLL为3557万人年，合计占总DALY 12%。结论与全球水平相比，无论是死亡还是DALY，中国人群归因于高血压的比例均较高，高血压造成的健康影响非常严重。
목적：정량고계중국인군고혈압적질병부담。방법사용2010년전구질병부담연구（GBD 2010）중국부분적방법화결과。이용인군평균수축압、인군사망、상잔손실수명년（YLL）、조서손실수명년（YLD）화상잔조정수명년（DALY）수거，이급교정료회귀희석계수적혈압여상관질병적련계강도수거，계산2010년중국인군귀인우고혈압적사망、YLL、YLD화DALY。결과재소유심혈관병사망화DALY중，고혈압적공헌위64.0%。2010년중국인고혈압사망공계204.3만례，기중남성115.4만례，녀성88.9만례；심혈관병사망200.7만례，만성신병사망3.5만례，유고혈압도치적사망점전부사망적24.6%。중국인군인고혈압조성적DALY고체3794만인년，기중남성위2332.6만인년，녀성위1461.4만인년；YLD위236.5만인년，YLL위3557만인년，합계점총DALY 12%。결론여전구수평상비，무론시사망환시DALY，중국인군귀인우고혈압적비례균교고，고혈압조성적건강영향비상엄중。
Objective To quantify the burden of disease related to high blood pressure in the Chinese population. Methods We used results from the Global Burden of Diseases,Injuries,and Risk Factors Study 2010 (GBD 2010) in China. Data for mean systolic blood pressure,burden of deaths,Years of Life Lost(YLLs),Years Lived with Disability(YLDs),disability-adjusted life years (DALYs),and relative risk were corrected for regression dilution bias to calculate the population impact fractions and estimate the attributable deaths and DALYs. Results Among all the deaths due to cardiovascular diseases and DALYs,64.0%of them were caused by high blood pressure. In 2010,a total number of 2.043 million deaths were caused by high blood pressure,including 1.154 million males. 2.007 million deaths were due to cardiovascular diseases,35 000 due to chronic kidney diseases. Deaths caused by high blood pressure accounted for 24.6%of all the deaths. In total,37.94 million person-years DALYs were caused by high blood pressure,of which 23.33 million person-years were males and 14.61 million person-years were females. There were 2.365 million person-years of YLDs and 35.57 million person-years of YLLs,which both accounted for 12% of the total DALYs. Conclusion Compared to the global results of GBD 160,on either deaths or DALYs,the proportion attributable to high blood pressure were quite high for a country like China. The health effects caused by high blood pressure seemed to be quite serious which called for attention.