CAJ | 학술논문

目的探讨莉芙敏片用于治疗早期子宫内膜癌患者术后绝经相关症状的有效性和安全性。方法选取2011年1月～2012年5月来我院治疗的因子宫内膜癌Ⅰ期术后出现绝经相关症状的患者80例，随机分为对照组和观察组，对照组不服药，观察组口服0.28g的莉芙敏片，2次/天，共计12周，随访1年，比较两组的绝经指数总分、骨密度及肿瘤复发率和死亡率。结果经过12周治疗，观察组的KMI评分明显降低，骨密度明显增加，与治疗前及观察组比较均有统计学差异（P<0.05）。两组肿瘤复发率和死亡率不具有显著性差异（P>0.05）。结论莉芙敏可用于治疗早期子宫内膜癌患者术后的绝经相关症状，且不增加肿瘤的复发率。
목적탐토리부민편용우치료조기자궁내막암환자술후절경상관증상적유효성화안전성。방법 선취2011년1월～2012년5월래아원치료적인자궁내막암Ⅰ기술후출현절경상관증상적환자80례，수궤분위대조조화관찰조，대조조불복약，관찰조구복0.28g적리부민편，2차/천，공계12주，수방1년，비교량조적절경지수총분、골밀도급종류복발솔화사망솔。결과경과12주치료，관찰조적KMI평분명현강저，골밀도명현증가，여치료전급관찰조비교균유통계학차이（P<0.05）。량조종류복발솔화사망솔불구유현저성차이（P>0.05）。결론 리부민가용우치료조기자궁내막암환자술후적절경상관증상，차불증가종류적복발솔。
Objective: To explore the effectiveness and safety of remifemin tablets for the treatment of menopause symptoms related to early endometrial carcinoma patients after operation.Methods: Select 80 cases of patienta with menopause symptoms after endometrium carcinomaⅠ period operation in our treatment from Jan 2011 to May 2012, they were randomly divided into control group and observation group, control group do not take any medicine, the observation group take orally 0.28 g of remifemin tablet, twice one day, 12 weeks in total ,follow-up of 1 year, compared with postmenopausal index score, bone mineral density and tumor recurrence rate and mortality of two groups.Results: After 12 weeks of treatment, KMI score of observation group decrease significantly, bone mineral density increased significantly, compare to before treatment and observation group ,there are statistical difference (P < 0.05). Tumor recurrence rate and mortality of two groups has no significant difference (P > 0.05).Conclusion: Remifemin tablet can cure the menopausal symptoms in patients with early endometrial cancer after operation ,without increasing the risk of tumor recurrence.