CAJ | 학술논문

目的探讨阿卡波糖对老年冠心病患者餐后生理参数的影响。方法回顾性分析我院2010年1月～2012年1月间收治的98例老年冠心病患者的临床资料，所有患者均给予口服阿卡波糖，观察用药后餐前餐后血压、心率、血糖及血脂变化情况，记录心血管事件发生情况。结果本组98例老年冠心病患者经口服阿卡波糖治疗后，餐前餐后的血压、心率、血糖波动情况较小，与治疗前相比差异有统计学意义（P<0.05）。治疗后2例患者发生急性心肌梗死，1例患者出现新发心绞痛，1例患者发生心力衰竭，心血管事件发生率为4.1%。结论阿卡波糖对改善冠心病患者的餐后生理参数，避免或减少心血管事件发生具有重要的意义，值得临床进一步推广使用。
목적탐토아잡파당대노년관심병환자찬후생리삼수적영향。방법회고성분석아원2010년1월～2012년1월간수치적98례노년관심병환자적림상자료，소유환자균급여구복아잡파당，관찰용약후찬전찬후혈압、심솔、혈당급혈지변화정황，기록심혈관사건발생정황。결과본조98례노년관심병환자경구복아잡파당치료후，찬전찬후적혈압、심솔、혈당파동정황교소，여치료전상비차이유통계학의의（P<0.05）。치료후2례환자발생급성심기경사，1례환자출현신발심교통，1례환자발생심력쇠갈，심혈관사건발생솔위4.1%。결론아잡파당대개선관심병환자적찬후생리삼수，피면혹감소심혈관사건발생구유중요적의의，치득림상진일보추엄사용。
Objective To investigate the effect of acarbose on physiological parameters in elderly patients with coronary heart disease after meal. Methods A retrospective analysis of the clinical data about 98 cases with elderly patients with coronary heart disease in our hospital from 2010 January to 2012 January was operated, all patients were given oral acarbose, observed blood pressure, heart rate, blood glucose and blood lipid changes before and after meal, recorded cardiovascular events. Results 98 cases of elderly patients with coronary heart disease after oral administration of acarbose treatment, blood pressure, heart rate, blood glucose fluctuation before and after meal was smaller, compared with before treatment, the difference was statistically significant ( P<0.05 ). The occurrence of acute myocardial infarction in 2 patients after the treatment, 1 cases occured new onset angina, heart failure occurred in 1 patients, the incidence rate of cardiovascular events was 4.1%. Conclusion acarbose on improving physiological parameters and avoiding or reducing the incidence of cardiovascular events has important significance, it is worthy of further promotion.