现代诊断与治疗
現代診斷與治療
현대진단여치료
MODERN DIAGNOSIS AND TREATMENT
2014年
3期
524-525
,共2页
老年痴呆%精神行为症状%奥氮平
老年癡呆%精神行為癥狀%奧氮平
노년치태%정신행위증상%오담평
Senile dementia%Behavioral and psychological symptoms%Olanzapine
目的:探讨奥氮平治疗老年痴呆患者的疗效。方法将98例老年痴呆症患者分为两组,研究组50例给予奥氮平治疗,对照组48例给予利培酮治疗。结果研究组总有效率为94.00%,不良反应发生率为12.00%,对照组总有效率为68.75%,不良反应发生率为33.33%,研究组研究组总有效率较高,不良反应发生率较低,治疗后PANSS量表评分下降更明显,两组差异有统计学意义(P<0.05)。结论奥氮平治疗老年痴呆患者精神行为症状,可取得较好的疗效,PANSS量表评分下降明显。
目的:探討奧氮平治療老年癡呆患者的療效。方法將98例老年癡呆癥患者分為兩組,研究組50例給予奧氮平治療,對照組48例給予利培酮治療。結果研究組總有效率為94.00%,不良反應髮生率為12.00%,對照組總有效率為68.75%,不良反應髮生率為33.33%,研究組研究組總有效率較高,不良反應髮生率較低,治療後PANSS量錶評分下降更明顯,兩組差異有統計學意義(P<0.05)。結論奧氮平治療老年癡呆患者精神行為癥狀,可取得較好的療效,PANSS量錶評分下降明顯。
목적:탐토오담평치료노년치태환자적료효。방법장98례노년치태증환자분위량조,연구조50례급여오담평치료,대조조48례급여리배동치료。결과연구조총유효솔위94.00%,불량반응발생솔위12.00%,대조조총유효솔위68.75%,불량반응발생솔위33.33%,연구조연구조총유효솔교고,불량반응발생솔교저,치료후PANSS량표평분하강경명현,량조차이유통계학의의(P<0.05)。결론오담평치료노년치태환자정신행위증상,가취득교호적료효,PANSS량표평분하강명현。
Objective To investigate the efficacy of olanzapine in the treatment of senile dementia. Methods 98 cases of senile dementia patients were divided into two groups, 50 patients in research group were treated with olanzapine, 48 cases in control group were given risperidone. Results The to-tal effective rate of research group was 94.00%, the incidence rate of adverse reaction was 12.00%, to-tal effective rate of the control group was 68.75%, the incidence rate of adverse reaction was 33.33%. The research group has higher efficiency, lower incidence rate of adverse reaction. After treatment, PANSS score decreased more obviously, there was a significant difference between the two groups.(P<0.05). Conclusion Olanzapine in the treatment of behavioral and psychological symptoms of senile de-mentia, can achieve better curative effect, PANSS score decreased significantly.