CAJ | 학술논문

目的探讨舒芬太尼与芬太尼对神经外科患者手术麻醉的临床效果。方法选取黄石市阳新县三医院2009年8月至2012年12月神经外科择期全麻下开颅手术患者80例，随机将患者分为舒芬太尼组（n＝40）与芬太尼组（n＝40），比较两种麻醉药物对患者血流动力学、麻醉相关时间、术后疼痛程度的影响。结果两组麻醉诱导后血流动力学指标均较诱导前明显下降（P＜0．05）。芬太尼组气管插管前及气管插管后3 min ，患者的血流动力学变化均较舒芬太尼明显上升（P＜0．05）。舒芬太尼组患者术后拔管时间、意识恢复时间较芬太尼组明显缩短（P＜0．05）；拔管后5 h舒芬太尼组患者疼痛程度明显低于芬太尼组。结论应用舒芬太尼麻醉的患者术中血流动力学指标稳定，镇痛作用强，术后拔管时间短、意识恢复快。
목적탐토서분태니여분태니대신경외과환자수술마취적림상효과。방법선취황석시양신현삼의원2009년8월지2012년12월신경외과택기전마하개로수술환자80례，수궤장환자분위서분태니조（n＝40）여분태니조（n＝40），비교량충마취약물대환자혈류동역학、마취상관시간、술후동통정도적영향。결과량조마취유도후혈류동역학지표균교유도전명현하강（P＜0．05）。분태니조기관삽관전급기관삽관후3 min ，환자적혈류동역학변화균교서분태니명현상승（P＜0．05）。서분태니조환자술후발관시간、의식회복시간교분태니조명현축단（P＜0．05）；발관후5 h서분태니조환자동통정도명현저우분태니조。결론응용서분태니마취적환자술중혈류동역학지표은정，진통작용강，술후발관시간단、의식회복쾌。
Objective To investigate the anaesthetic effect of sufentanil and fentanyl in neurosurgical surgery . Methods 80 patients receiving craniotomy operation from Aug .2009 to Dec .2012 were randomly divided into sufen-tanil group(n=40) and fentanyl group(n=40) .The effects on hemodynamics ,anesthesia related time and postopera-tive pain were compared between the two groups .Results Detected results of hemodynamics indicators significantly decreased after anesthesia in the two groups(P<0 .05) .Hemodynamic indexes in sufentanil group increased more ob-viously than fentanyl group before tracheal intubation and 3 minutes after tracheal intubation (P<0 .05) .Extubation time and consciousness recovery time of sufentanil group were significantly shorter than fentanyl group (P<0 .05) . The pain degree of 5 hours after extubation was significantly lower in sufentanil group than fentanyl group (P<0 .05) .Conclusion Sufentanil anesthesia might be with less influence on hemodynamics ,strong analgesic effect and fast consciousness recovery after extubation .