CAJ | 학술논문

目的探讨血清鳞状细胞癌相关抗原（SCCAg ）在鼻咽癌人群的表达及其与鼻咽癌发生远端转移的关系。方法根据TNM分期有无发生远端转移分为M1、M0组。采用酶联免疫检测法，检测鼻咽癌患者M0组90例，M1组33例血清中的SCCAg表达水平。结果鼻咽癌M0组SCCAg阳性率为5．56％，M1组SCCAg阳性率为27．27％，两组比较差异有统计学意义（P＜0．05）。结论 SCCAg作为鼻咽癌的筛查指标敏感度偏低，而对鼻咽癌是否发生远端转移有一定的临床意义。
목적탐토혈청린상세포암상관항원（SCCAg ）재비인암인군적표체급기여비인암발생원단전이적관계。방법근거TNM분기유무발생원단전이분위M1、M0조。채용매련면역검측법，검측비인암환자M0조90례，M1조33례혈청중적SCCAg표체수평。결과비인암M0조SCCAg양성솔위5．56％，M1조SCCAg양성솔위27．27％，량조비교차이유통계학의의（P＜0．05）。결론 SCCAg작위비인암적사사지표민감도편저，이대비인암시부발생원단전이유일정적림상의의。
Objective To investigate the correlation between squamous cell carcinoma antigen (SCCAg) with distant metastasis of nasopharyngeal carcinoma (NPC) .Methods NPC patients were divided into M0 group for 90 cases and M1 group for 33 cases ,according to TNM staging and distant metastasis ,and detected for serum SCCAg level .Results The positive rates of SCCAg in M0 and M1 group were 5 .56% and 27 .27% ,with statistical difference between the two groups (P<0 .05) .Conclusion SCCAg might be not sensitive for the screening of NPC ,but could be with clinical significance for the diagnosis of distant metastasis .