中国妇幼健康研究
中國婦幼健康研究
중국부유건강연구
CHINESE JOURNAL OF MATERNAL AND CHILD HEALTH RESEARCH
2014年
2期
252-253,262
,共3页
亚临床甲状腺功能减退%妊娠期糖尿病%妊娠期高血压%妊娠结局
亞臨床甲狀腺功能減退%妊娠期糖尿病%妊娠期高血壓%妊娠結跼
아림상갑상선공능감퇴%임신기당뇨병%임신기고혈압%임신결국
subclinical hypothyroidism (SCH)%gestational diabetes mellitus (GDM)%hypertensive disorders in pregnancy%pregnancy outcomes
目的：研究亚临床甲状腺功能减退（ SCH）对孕期并发症及妊娠结局的影响。方法选取经甲状腺功能筛查诊断为SCH的孕妇1053例（ SCH组），正常孕妇3899例（对照组），比较各组TSH、FT4、TPOAb，孕期并发症及妊娠结局情况。结果SCH组的TSH水平及TPOAb阳性率均高于对照组（t＝39．001，P＜0．01；χ2＝40．753，P＜0．01）。 SCH组的早产率及新生儿窒息率高于对照组（χ2＝8．638，P＜0．05；χ2＝22．209，P＜0．01），SCH组新生儿低出生体重率高于对照组，但无统计学意义（χ2＝2．323，P＞0．05）。结论 SCH是孕期常见病，可能与流产、早产等妊娠不良结局的发生相关，应重视妊娠妇女的SCH筛查。
目的：研究亞臨床甲狀腺功能減退（ SCH）對孕期併髮癥及妊娠結跼的影響。方法選取經甲狀腺功能篩查診斷為SCH的孕婦1053例（ SCH組），正常孕婦3899例（對照組），比較各組TSH、FT4、TPOAb，孕期併髮癥及妊娠結跼情況。結果SCH組的TSH水平及TPOAb暘性率均高于對照組（t＝39．001，P＜0．01；χ2＝40．753，P＜0．01）。 SCH組的早產率及新生兒窒息率高于對照組（χ2＝8．638，P＜0．05；χ2＝22．209，P＜0．01），SCH組新生兒低齣生體重率高于對照組，但無統計學意義（χ2＝2．323，P＞0．05）。結論 SCH是孕期常見病，可能與流產、早產等妊娠不良結跼的髮生相關，應重視妊娠婦女的SCH篩查。
목적：연구아림상갑상선공능감퇴（ SCH）대잉기병발증급임신결국적영향。방법선취경갑상선공능사사진단위SCH적잉부1053례（ SCH조），정상잉부3899례（대조조），비교각조TSH、FT4、TPOAb，잉기병발증급임신결국정황。결과SCH조적TSH수평급TPOAb양성솔균고우대조조（t＝39．001，P＜0．01；χ2＝40．753，P＜0．01）。 SCH조적조산솔급신생인질식솔고우대조조（χ2＝8．638，P＜0．05；χ2＝22．209，P＜0．01），SCH조신생인저출생체중솔고우대조조，단무통계학의의（χ2＝2．323，P＞0．05）。결론 SCH시잉기상견병，가능여유산、조산등임신불량결국적발생상관，응중시임신부녀적SCH사사。
Objective To investigate the influence of subclinical hypothyroidism ( SCH ) on complications and pregnancy outcomes . Methods A retrospective chart review was performed on 1 053 pregnant women with SCH ( SCH group ) and 3 899 pregnant women with normal thyroid function ( control group ) diagnosed by serum thyroid function screening .The following parameters of two groups were compared:serum levels of TSH, FT4 and TPOAb, maternal complications and pregnancy outcomes .Results Serum TSH level of SCH group was higher than control group (t=39.001,P<0.01) and TPOAb positive rate was higher in SCH group (χ2 =40.753,P<0.01). The incidences of premature delivery and neonatal asphyxia were higher in SCH group (χ2 =8.638,P<0.05;χ2 =22.209,P<0.01).The incidence of neonatal low birth weight was higher in SCH group , but the difference showed no statistical significance (χ2 =2.323,P>0.05).Conclusion SCH is common in pregnant women .It maybe contribute to adverse pregnancy outcomes such as abortion and premature.More attention should be paid on SCH screening in pregnant women .
