中外健康文摘
中外健康文摘
중외건강문적
WORLD HEALTH DIGEST
2013年
23期
410-411
,共2页
促红细胞生成素%新生儿缺氧缺血性脑病
促紅細胞生成素%新生兒缺氧缺血性腦病
촉홍세포생성소%신생인결양결혈성뇌병
recombinant human erythropoietin%neonatal hypoxic-ischemic encephalopathy
目的评价重组人促红细胞生成素( rhEPO )对新生儿缺氧缺血性脑病的疗效。方法取新生儿缺氧缺血性脑病( HIE)患儿110例，随机分为治疗组55例及观察组55例，治疗后1周及2周对分别两组患儿进行NBNA评分，治疗后3、6个月时分别进行智能发育测试(CDCC)。结果与对照组相比，治疗组的NBNA评分及智能发育测试均明显升高.差异有统计学意义( P均<O.05)。结论 rh EPO 对新生儿HIE的近期疗效和长期预后有重大意义。
目的評價重組人促紅細胞生成素( rhEPO )對新生兒缺氧缺血性腦病的療效。方法取新生兒缺氧缺血性腦病( HIE)患兒110例，隨機分為治療組55例及觀察組55例，治療後1週及2週對分彆兩組患兒進行NBNA評分，治療後3、6箇月時分彆進行智能髮育測試(CDCC)。結果與對照組相比，治療組的NBNA評分及智能髮育測試均明顯升高.差異有統計學意義( P均<O.05)。結論 rh EPO 對新生兒HIE的近期療效和長期預後有重大意義。
목적평개중조인촉홍세포생성소( rhEPO )대신생인결양결혈성뇌병적료효。방법취신생인결양결혈성뇌병( HIE)환인110례，수궤분위치료조55례급관찰조55례，치료후1주급2주대분별량조환인진행NBNA평분，치료후3、6개월시분별진행지능발육측시(CDCC)。결과여대조조상비，치료조적NBNA평분급지능발육측시균명현승고.차이유통계학의의( P균<O.05)。결론 rh EPO 대신생인HIE적근기료효화장기예후유중대의의。
Objective To evaluate the neural protective effect of neonatal hypoxic-ischemic encephalopathy (HIE) treated with recombinant human erythropoietin (rhEPO). Method 110 neonates with HIE were randomly divided into t reated group(n=55) and control group(n=55). Neonatal behavioral neurological assessment(NBNA)was evaluated at d7 and d14, while infants’ intelligence scale of Chinese children development center(CDCC) was evaluated at 3m and 6m. Result:NBNA and infants’ intelligence scale of CDCC scores were significantly higher in treated group than that in control group. There were significant statistical difference between two groups(P<0.05). Conclusion: Therapy with rhEPO on neonatal HIE infants can promote neurological recovery and long-term prognosis.
