CAJ | 학술논문

目的探索精神因素对胃食管阀瓣（GEFV）功能的影响。方法随机抽取2008年4月至2010年7月我院消化内科218例因上消化道症状行常规内镜检查的病人（排除食管癌、胃癌、食管静脉曲张及各种病因导致的幽门梗阻）。其中男141人、女77人，年龄17岁—85岁。首先，在行内镜检查前填写zung抑郁自评表（SDS）和焦虑自评表（SAS），然后，在检查中进行GEFV分级。最后，对218例病人年龄、性别比例与GEFV分级的关系、精神因素与GEFV分级的关系进行相关性分析。结果精神心理异常（SDS≥50%或SAS≥50分）的胃食管反流病（GERD）患者GEFV的分级明显升高，Ⅲ+Ⅳ级发生率明显高于Ⅰ+Ⅱ级的发生率（P<0.05）。结论精神因素有可能通过其在内脏感觉传导通路的信号传导，引起胃食管阀瓣的功能异常，从而导致GERD的发生。
목적탐색정신인소대위식관벌판（GEFV）공능적영향。방법수궤추취2008년4월지2010년7월아원소화내과218례인상소화도증상행상규내경검사적병인（배제식관암、위암、식관정맥곡장급각충병인도치적유문경조）。기중남141인、녀77인，년령17세—85세。수선，재행내경검사전전사zung억욱자평표（SDS）화초필자평표（SAS），연후，재검사중진행GEFV분급。최후，대218례병인년령、성별비례여GEFV분급적관계、정신인소여GEFV분급적관계진행상관성분석。결과정신심리이상（SDS≥50%혹SAS≥50분）적위식관반류병（GERD）환자GEFV적분급명현승고，Ⅲ+Ⅳ급발생솔명현고우Ⅰ+Ⅱ급적발생솔（P<0.05）。결론정신인소유가능통과기재내장감각전도통로적신호전도，인기위식관벌판적공능이상，종이도치GERD적발생。
Objective Explore the impact of mental factors on the Gastroesophageal Flap Valve(GEFV).liang Method Randomly select 218 cases of patients by the result of routine endoscopy for upper gastrointestinal symptoms from April 2008 to July 2010. These patients suffered from pyloric obstruction that was not caused by esophageal cancer, gastric cancer, esophageal varices and other related diseases. There are 141 men and 77 women aged from 17 years old to 85 years old. First, before endoscopy the patients filled zung self-assessment depression sheets (SDS) and self-assessment anxiety table (SAS). Then, they were graded GEFV during inspection. And last, analysis the relationship between age, sex ratio and GEFV grading, and the relationship between mental factors and GEFV grading of all the 218 patients. Resluts The GEFV grading of gastroesophageal reflux disease(GERD)patients(SDS ≥ 50% or SAS ≥ 50 points) who have psychological abnormalities is significantly higher; the incidence of level III+IV was significantly higher than that of I+II (P<0.05). Conclusion It is most likely that the mental factors in the form of signal conducted via visceral sensory pathways cause the dysfunction of GEFV, and then result in the occurrence of GERD.