中外健康文摘
中外健康文摘
중외건강문적
WORLD HEALTH DIGEST
2013年
27期
87-88
,共2页
西酞普兰%利培酮%脑卒中后抑郁
西酞普蘭%利培酮%腦卒中後抑鬱
서태보란%리배동%뇌졸중후억욱
Citalopram%Risperidone%post-strok depression
目的探讨西酞普兰合用利培酮治疗脑卒中后抑郁的疗效。方法将89例脑卒中后抑郁患者随机分成二组，分别给予西酞普兰和安慰剂与西酞普兰合用利培酮治疗6周，以HAMD及HAMA二种量表观察疗效，以TESS观察副作用。结果二组间HAMD和HAMA于第1、2、6周末减分率比较均有显著性差异（P<0.05～0.01）。TESS各周差异均不明显。结论西酞普兰合用利培酮治疗脑卒中后抑郁的疗效优于西酞普兰，且耐受性好。
目的探討西酞普蘭閤用利培酮治療腦卒中後抑鬱的療效。方法將89例腦卒中後抑鬱患者隨機分成二組，分彆給予西酞普蘭和安慰劑與西酞普蘭閤用利培酮治療6週，以HAMD及HAMA二種量錶觀察療效，以TESS觀察副作用。結果二組間HAMD和HAMA于第1、2、6週末減分率比較均有顯著性差異（P<0.05～0.01）。TESS各週差異均不明顯。結論西酞普蘭閤用利培酮治療腦卒中後抑鬱的療效優于西酞普蘭，且耐受性好。
목적탐토서태보란합용리배동치료뇌졸중후억욱적료효。방법장89례뇌졸중후억욱환자수궤분성이조，분별급여서태보란화안위제여서태보란합용리배동치료6주，이HAMD급HAMA이충량표관찰료효，이TESS관찰부작용。결과이조간HAMD화HAMA우제1、2、6주말감분솔비교균유현저성차이（P<0.05～0.01）。TESS각주차이균불명현。결론서태보란합용리배동치료뇌졸중후억욱적료효우우서태보란，차내수성호。
Objective:To explore the effect of combine citalopram with risperidone in the treatment of post-trok depression(PSD). Methods:89 patients with PSD were randomly assigned into two groups treated respectively,such as combine citalopram with risperidone and citalopram combined with placebo for 6 weeks in order to evaluate efficacy and side effects with HAMD,HAMA and TESS after 1、2、6 week. Results:There were differences of decreased scores of HAMD,HAMA between the two groups patients after 1、2、6 week respectively (p<0.05~0.01).There were no differences of scores of TESS between the two groups patients after 1、2、6 week respectively. Conlusion:Combine citalopram with risperidone was much better than citalopram combined with placebo,the former was well tolerated.
