中外医学研究
中外醫學研究
중외의학연구
CHINESE AND FOREIGN MEDICAL RESEARCH
2013年
29期
11-12
,共2页
无创正压通气%可必特%重症支气管哮喘%临床疗效
無創正壓通氣%可必特%重癥支氣管哮喘%臨床療效
무창정압통기%가필특%중증지기관효천%림상료효
Non-invasive positive pressure ventilation%Combivent%Severe bronchial asthma%Clinical effect
目的：探讨无创正压通气并经管道雾化吸入可必特治疗重症支气管哮喘的疗效。方法：选择2011年6月-2013年1月在广东省农垦中心医院呼吸内科住院的重症支气管哮喘患者90例，随机分为治疗组和对照组，每组45例。对照组：予吸氧、抗感染、激素、解痉、平喘及化痰等常规治疗。治疗组：在常规治疗的基础上，同时应用经鼻(面)罩无创正压通气并经管道雾化吸入可必特治疗。观察两组患者的临床疗效，并记录两组患者治疗前及治疗6 h后其呼吸频率、血气分析指标的变化。结果：治疗组有效率明显高于对照组，差异有统计学意义(P<0.001)；两组患者在治疗前的呼吸频率、血气分析指标等差异无统计学意义(P>0.05)，治疗6 h后治疗组较对照组呼吸频率、动脉二氧化碳分压(PaCO2)降低，动脉血氧分压(PaO2)及血氧饱和度(SaO2)提高，差异均有统计学意义(P<0.05)。结论：无创正压通气并经管道雾化吸入可必特能有效治疗重症支气管哮喘，值得临床推广和应用。
目的：探討無創正壓通氣併經管道霧化吸入可必特治療重癥支氣管哮喘的療效。方法：選擇2011年6月-2013年1月在廣東省農墾中心醫院呼吸內科住院的重癥支氣管哮喘患者90例，隨機分為治療組和對照組，每組45例。對照組：予吸氧、抗感染、激素、解痙、平喘及化痰等常規治療。治療組：在常規治療的基礎上，同時應用經鼻(麵)罩無創正壓通氣併經管道霧化吸入可必特治療。觀察兩組患者的臨床療效，併記錄兩組患者治療前及治療6 h後其呼吸頻率、血氣分析指標的變化。結果：治療組有效率明顯高于對照組，差異有統計學意義(P<0.001)；兩組患者在治療前的呼吸頻率、血氣分析指標等差異無統計學意義(P>0.05)，治療6 h後治療組較對照組呼吸頻率、動脈二氧化碳分壓(PaCO2)降低，動脈血氧分壓(PaO2)及血氧飽和度(SaO2)提高，差異均有統計學意義(P<0.05)。結論：無創正壓通氣併經管道霧化吸入可必特能有效治療重癥支氣管哮喘，值得臨床推廣和應用。
목적：탐토무창정압통기병경관도무화흡입가필특치료중증지기관효천적료효。방법：선택2011년6월-2013년1월재광동성농은중심의원호흡내과주원적중증지기관효천환자90례，수궤분위치료조화대조조，매조45례。대조조：여흡양、항감염、격소、해경、평천급화담등상규치료。치료조：재상규치료적기출상，동시응용경비(면)조무창정압통기병경관도무화흡입가필특치료。관찰량조환자적림상료효，병기록량조환자치료전급치료6 h후기호흡빈솔、혈기분석지표적변화。결과：치료조유효솔명현고우대조조，차이유통계학의의(P<0.001)；량조환자재치료전적호흡빈솔、혈기분석지표등차이무통계학의의(P>0.05)，치료6 h후치료조교대조조호흡빈솔、동맥이양화탄분압(PaCO2)강저，동맥혈양분압(PaO2)급혈양포화도(SaO2)제고，차이균유통계학의의(P<0.05)。결론：무창정압통기병경관도무화흡입가필특능유효치료중증지기관효천，치득림상추엄화응용。
Objective:To explore the clinical curative effect that non-invasive positive pressure ventilation jointed atomization inhalation of combivent treated severe bronchial asthma.Method:90 patients were randomly divided into treatment group and control group,which had been diagnosed as severe bronchial asthma in the Respiration Department of our hospital from June 2011 to January 2013. Each group contained 45 patients. The methods of treatment in control group were routine treatments,such as using oxygen,anti-infection,glucocorticoid,spasmolysis,relieving asthma and reducing phlegm. Excepting the routine treatments,treatment group also added non-invasive positive pressure ventilation jointed atomization inhalation of combivent. we observed the clinical effects in two groups. In addition,we recorded the changes of respiratory rate and the indexes of blood gas analysis before the therapy and after 6 hours of the therapy.Result:The effective rate in the treatment group was significantly higher than in the control group(P<0.001). The changes of respiratory rate and the indexes of blood gas analysis between the two groups before the therapy were not significant(P>0.05). However,after 6 hours of the therapy,respiratory rate and PaCO2 in treatment group were significantly lower compared to control group(P<0.05). On the contrary,PaO2 and SaO2 were significantly higher in treatment group (P<0.05).Conclusion:Non-invasive positive pressure ventilation jointed atomization inhalation of combivent have an obviously positive effect in the therapy of severe bronchial asthma,and need further promotion and application in the clinical work.
