CAJ | 학술논문

目的：探讨三阴性乳腺癌（T NBC ）的乳腺摄影、M RI影像学特点和临床病理特征，并与非三阴性乳腺癌（N T NBC ）进行比较。方法选择150例经手术病理证实的乳腺癌患者，根据术后免疫组化染色，分为三阴性乳腺癌组（T NBC组，41例）和非三阴性乳腺癌组（N T NBC组，109例），分析并比较病灶的乳腺摄影、M RI影像学表现及临床病理特征，两组乳腺摄影及M R检查中乳腺密度、病灶钙化、形态、边缘、T2信号、内部强化等比较采用卡方检验。结果 T NBC组腋窝淋巴结转移率为512．％，N T NBC组腋窝淋巴结转移率为477．％，两组差异无统计学意义。病理分型：T NBC组浸润性导管癌32例（780．％），N T NBC组浸润性导管癌102例（936．％），两组差异有统计学意义。T NBC组乳腺摄影最常见表现为边缘清晰（18/41，439．％）、圆形或类圆形（19/41，463．％）、少钙化单纯肿块（34/41，829．％）。TNBC组MRI特征性征象表现为形状不规则（22/41，537．％）、T2WI序列呈明显高信号（20/41，488．％）、环状强化（28/41，680．％）、时间信号曲线呈持续上升型强化曲线（28/41，683．％）。T NBC组与NTNBC组乳腺摄影肿块钙化、肿块形态及边缘表现差异有统计学意义（P ＜00．5）。两组MRI检查 T2信号及病灶内部强化方式差异具有统计学意义。结论乳腺摄影、M RI影像表现及病理特征有助于诊断T NBC。
목적：탐토삼음성유선암（T NBC ）적유선섭영、M RI영상학특점화림상병리특정，병여비삼음성유선암（N T NBC ）진행비교。방법선택150례경수술병리증실적유선암환자，근거술후면역조화염색，분위삼음성유선암조（T NBC조，41례）화비삼음성유선암조（N T NBC조，109례），분석병비교병조적유선섭영、M RI영상학표현급림상병리특정，량조유선섭영급M R검사중유선밀도、병조개화、형태、변연、T2신호、내부강화등비교채용잡방검험。결과 T NBC조액와림파결전이솔위512．％，N T NBC조액와림파결전이솔위477．％，량조차이무통계학의의。병리분형：T NBC조침윤성도관암32례（780．％），N T NBC조침윤성도관암102례（936．％），량조차이유통계학의의。T NBC조유선섭영최상견표현위변연청석（18/41，439．％）、원형혹류원형（19/41，463．％）、소개화단순종괴（34/41，829．％）。TNBC조MRI특정성정상표현위형상불규칙（22/41，537．％）、T2WI서렬정명현고신호（20/41，488．％）、배상강화（28/41，680．％）、시간신호곡선정지속상승형강화곡선（28/41，683．％）。T NBC조여NTNBC조유선섭영종괴개화、종괴형태급변연표현차이유통계학의의（P ＜00．5）。량조MRI검사 T2신호급병조내부강화방식차이구유통계학의의。결론유선섭영、M RI영상표현급병리특정유조우진단T NBC。
Objective To investigate the mammography and MRI imaging findings of triple-negative breast cancer and to compare the results with characteristics of non-TNBC breast cancer .Methods Mammogra-phy and MRI imaging findings of 150 patients with pathologically confirmed triple-negative breast cancer (n =41) ,non-triple-negative breast cancer (n =109) were retrospectively reviewed .The breast density , the lesions focal calcified ,shape ,edge ,T2 signal and the enhancement mode between the two groups were compared by chi-square test .Results There were 41(27 3.% ) TNBC among 150 patients ,and the percent-age of lymph node metastasis in TNBC group (21/41 ,51 2.% ) was higher than that of NTNBC group (52/109 ,47 7.% ) .There were significant differences in pathological classification between the two groups (P <0 0.5) .On mammography ,triple-negative breast cancers usually presented with a round (19/41 ,46 3.% ) , mass less associated with calcifications (34/41 ,82 9.% ) ,more likely to have circumscribed margins (18/41 ,43 9.% ) .On MRI the triple-negative breast cancers usually presented with an irregular shape (22/41 , 53 7.% ) ,very high signal intensity on T2-weighted image (20/41 ,48 .8% ) ,rim enhancement (28/41 , 68 0.% ) and persistent enhancement pattern (28/41 , 68 .3% ) . There were statistically significant differences between the lesions form ,edge ,T2 signal ,enhancement mode in the mammography of the two groups of MRI (P < 0 .05) .Conclusion Mammography and MRI imaging findings and pathological features might be used for suggesting the diagnosis of triple-negative breast cancer .