中外健康文摘
中外健康文摘
중외건강문적
WORLD HEALTH DIGEST
2012年
30期
223-224
,共2页
急性胰腺炎%肿瘤坏死因子α%白细胞介素6
急性胰腺炎%腫瘤壞死因子α%白細胞介素6
급성이선염%종류배사인자α%백세포개소6
Acute pancreatitis%Tumor necrosis factor-α%Interleukin-6
目的探讨肿瘤坏死因子α(TNF-α)和白细胞介素6(IL-6)在急性胰腺炎(AP)患者中诊断及早期病情严重度评估中的价值.方法选取81例AP患者,分为轻症急性胰腺炎(MAP)组57例和重症急性胰腺炎(SAP)组24例,对SAP组和MAP组在入院后1h、24h、2d、3d、5d抽血测定TNF-α和IL-6,并对结果进行分析.结果 SAP组和MAP组在入院后1h、24h、3d检测TNF-α和IL-6的水平比较差异有统计学意义(P<0.05).结论血清TNF-α和IL-6水平变化与AP的发生发展密切相关,可作为AP病情变化和程度判断的参考指标,对AP早期严重度具有良好的预测作用.
目的探討腫瘤壞死因子α(TNF-α)和白細胞介素6(IL-6)在急性胰腺炎(AP)患者中診斷及早期病情嚴重度評估中的價值.方法選取81例AP患者,分為輕癥急性胰腺炎(MAP)組57例和重癥急性胰腺炎(SAP)組24例,對SAP組和MAP組在入院後1h、24h、2d、3d、5d抽血測定TNF-α和IL-6,併對結果進行分析.結果 SAP組和MAP組在入院後1h、24h、3d檢測TNF-α和IL-6的水平比較差異有統計學意義(P<0.05).結論血清TNF-α和IL-6水平變化與AP的髮生髮展密切相關,可作為AP病情變化和程度判斷的參攷指標,對AP早期嚴重度具有良好的預測作用.
목적탐토종류배사인자α(TNF-α)화백세포개소6(IL-6)재급성이선염(AP)환자중진단급조기병정엄중도평고중적개치.방법선취81례AP환자,분위경증급성이선염(MAP)조57례화중증급성이선염(SAP)조24례,대SAP조화MAP조재입원후1h、24h、2d、3d、5d추혈측정TNF-α화IL-6,병대결과진행분석.결과 SAP조화MAP조재입원후1h、24h、3d검측TNF-α화IL-6적수평비교차이유통계학의의(P<0.05).결론혈청TNF-α화IL-6수평변화여AP적발생발전밀절상관,가작위AP병정변화화정도판단적삼고지표,대AP조기엄중도구유량호적예측작용.
Objective:To explore the value dynamic changes of serum levels of tumor necrosis factor-α(TNF-α) and interleukin-6(IL-6)and to determine their predictive value for severity and prognosis of acute pancreatitis(AP).Methods 81 patients with acute pancreatitis were divided into mild acute pancreatitis group(MAP,n=57) and severe acute pancreatitis group(SAP,n=24),SAP and MAP Group at post admission 1h,24h,3d,dedicated TNF-a and IL-6,then analysed and contrasted the results.Results The chang of TNF-a and IL-6 levels at post-admission 1h、24h、2d、3d、5d between SAP and MAP duringhospitalization in patients were statistically significant difference(P<0.05).Conclusion Dynamic changes of the serum levels of TNF-α and IL-6 are related to the occurance and development of acute pancreatitis,and the serum levels of TNF-α and IL-6 on 3rd day may be a predictive index for severity and prognosis of acute pancreatitis.
